Rat hearts were perfused with [1, 2, 3, 4-13 C 4] palmitic acid (M+ 4), and the isotopic
patterns of myocardial acylcarnitines and acyl-CoAs were analyzed using ultra-HPLC …

Rat hearts perfused for up to 60min in the working mode with palmitate, but not with glucose,
resulted in substantial formation of palmitoylcarnitine and stearoylcarnitine. To test whether …

Regulation of fatty acid utilization was studied in the isolated, perfused rat heart. The effects
of increasing the concentration of perfusate fatty acid and the level of ventricular pressure …

In this work, an attempt was made to identify the reasons of impaired long-chain fatty acid
utilization that was previously described in volume-overloaded rat hearts. The most …

Palmitate metabolism was determined in isolated perfused hearts containing elevated levels
of coenzyme A (CoA). CoA levels were elevated by perfusing hearts with Krebs-Henseleit …

It has been proposed that the presence of increasing concentrations of fatty acids may
accelerate the development of ischaemic contracture and cardiac damage, and that this may …

The effect of carnitine on the uptake, oxidation, and esterification of circulating palmitate has
been studied with the isolated perfused rat heart. At concentrations of 0.5 m M and 5.0 m M …

Glycerophosphate and carnitine as competing acyl acceptors and the oxidation of different
long chain acylcarnitines in isolated mitochondria have been investigated. In the presence …

High concentrations of lactate and oxfenicine inhibit fatty acid oxidation in cardiac muscle.
The site of this inhibition was investigated in isolated perfused rat hearts. In hearts perfused …

The effects of glucose and lactate infusion on palmitate oxidation were compared with the
effect of 2-tetradecylglycidic acid (TDGA), an irreversible inhibitor of the carnitine …