[HTML][HTML] Adaptation of Pseudomonas aeruginosa in Cystic Fibrosis Airways Influences Virulence of Staphylococcus aureus In Vitro and Murine Models of Co …

R Baldan, C Cigana, F Testa, I Bianconi, M De Simone… - PloS one, 2014 - journals.plos.org
Cystic fibrosis (CF) airways disease represents an example of polymicrobial infection
whereby different bacterial species can interact and influence each other. In CF patients …

[HTML][HTML] Despite antagonism in vitro, Pseudomonas aeruginosa enhances Staphylococcus aureus colonization in a murine lung infection model

G Millette, JP Langlois, E Brouillette, EH Frost… - Frontiers in …, 2019 - frontiersin.org
Staphylococcus aureus and Pseudomonas aeruginosa are prevalent lung pathogens in
cystic fibrosis (CF). Whereas co-infection worsens the clinical outcome, prototypical strains …

[HTML][HTML] How bacterial adaptation to cystic fibrosis environment shapes interactions between Pseudomonas aeruginosa and Staphylococcus aureus

L Camus, P Briaud, F Vandenesch… - Frontiers in …, 2021 - frontiersin.org
Pseudomonas aeruginosa and Staphylococcus aureus are the two most prevalent bacteria
species in the lungs of cystic fibrosis (CF) patients and are associated with poor clinical …

[HTML][HTML] Cystic Fibrosis-Niche Adaptation of Pseudomonas aeruginosa Reduces Virulence in Multiple Infection Hosts

NI Lorè, C Cigana, I De Fino, C Riva, M Juhas… - PloS one, 2012 - journals.plos.org
The opportunistic pathogen Pseudomonas aeruginosa is able to thrive in diverse ecological
niches and to cause serious human infection. P. aeruginosa environmental strains are …

Molecular Epidemiology and Dynamics of Pseudomonas aeruginosa Populations in Lungs of Cystic Fibrosis Patients

L Jelsbak, HK Johansen, AL Frost… - Infection and …, 2007 - Am Soc Microbiol
The ability to establish lifelong persistent infections is a fundamental aspect of the
interactions between many pathogenic microorganisms and their mammalian hosts. One …

Pseudomonas aeruginosa Microevolution during Cystic Fibrosis Lung Infection Establishes Clones with Adapted Virulence

A Bragonzi, M Paroni, A Nonis, N Cramer… - American journal of …, 2009 - atsjournals.org
Rationale: During long-term lung infection in patients with cystic fibrosis (CF), Pseudomonas
aeruginosa strains develop mutations leading to clonal expansion. This microevolution is …

[HTML][HTML] Pseudomonas aeruginosa Diversification during Infection Development in Cystic Fibrosis Lungs—A Review

AM Sousa, MO Pereira - Pathogens, 2014 - mdpi.com
Pseudomonas aeruginosa is the most prevalent pathogen of cystic fibrosis (CF) lung
disease. Its long persistence in CF airways is associated with sophisticated mechanisms of …

Staphylococcus aureus Impacts Pseudomonas aeruginosa Chronic Respiratory Disease in Murine Models

C Cigana, I Bianconi, R Baldan… - The Journal of …, 2018 - academic.oup.com
Abstract Background Staphylococcus aureus and Pseudomonas aeruginosa are key
bacterial pathogens of the respiratory tract in patients with cystic fibrosis (CF). Although P …

[HTML][HTML] Tracking the immunopathological response to Pseudomonas aeruginosa during respiratory infections

C Cigana, NI Lorè, C Riva, I De Fino, L Spagnuolo… - Scientific reports, 2016 - nature.com
Repeated cycles of infections, caused mainly by Pseudomonas aeruginosa, combined with
a robust host immune response and tissue injury, determine the course and outcome of …

Novel experimental Pseudomonas aeruginosa lung infection model mimicking long‐term host–pathogen interactions in cystic fibrosis

C Moser, M Van Gennip, T Bjarnsholt, PØ Jensen… - Apmis, 2009 - Wiley Online Library
The dominant cause of premature death in patients suffering from cystic fibrosis (CF) is
chronic lung infection with Pseudomonas aeruginosa. The chronic lung infection often lasts …