A basic overview of multiple sclerosis immunopathology
N Grigoriadis, V Van Pesch - European journal of neurology, 2015 - Wiley Online Library
Multiple sclerosis (MS) is a multi‐component disease characterized by inflammation,
neurodegeneration and failure of central nervous system (CNS) repair mechanisms …
neurodegeneration and failure of central nervous system (CNS) repair mechanisms …
Immunopathology of multiple sclerosis
CA Dendrou, L Fugger, MA Friese - Nature Reviews Immunology, 2015 - nature.com
Two decades of clinical experience with immunomodulatory treatments for multiple sclerosis
point to distinct immunological pathways that drive disease relapses and progression. In …
point to distinct immunological pathways that drive disease relapses and progression. In …
Pathology of multiple sclerosis and related inflammatory demyelinating diseases
A Kutzelnigg, H Lassmann - Handbook of clinical neurology, 2014 - Elsevier
This article provides a comprehensive overview of the pathology of multiple sclerosis (MS),
including recent insights into its molecular neuropathology and immunology. It shows that all …
including recent insights into its molecular neuropathology and immunology. It shows that all …
Pathology of multiple sclerosis
M Kipp, P van der Valk, S Amor - CNS & Neurological …, 2012 - ingentaconnect.com
Pathological examination of the affected human tissue is key to understanding the possible
mechanisms operating in the disease. In multiple sclerosis (MS), studies of central nervous …
mechanisms operating in the disease. In multiple sclerosis (MS), studies of central nervous …
Immunopathology of multiple sclerosis
EJ Fox - Neurology, 2004 - AAN Enterprises
Multiple sclerosis (MS) is an immune-mediated disease of the CNS that is characterized by
inflammation, demyelination, and axon loss. The inflammation in MS appears to be caused …
inflammation, demyelination, and axon loss. The inflammation in MS appears to be caused …
Update on inflammation, neurodegeneration, and immunoregulation in multiple sclerosis: therapeutic implications
JL Bennett, O Stüve - Clinical neuropharmacology, 2009 - journals.lww.com
Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease
of the central nervous system of uncertain etiology. There is consensus that a dysregulated …
of the central nervous system of uncertain etiology. There is consensus that a dysregulated …
Multiple sclerosis: an immune or neurodegenerative disorder?
BD Trapp, KA Nave - Annu. Rev. Neurosci., 2008 - annualreviews.org
Multiple sclerosis (MS) is an inflammatory-mediated demyelinating disease of the human
central nervous system. The clinical disease course is variable, usually starts with reversible …
central nervous system. The clinical disease course is variable, usually starts with reversible …
Multiple sclerosis is an inflammatory T-cell–mediated autoimmune disease
HL Weiner - Archives of neurology, 2004 - jamanetwork.com
The etiology and pathogenesis of multiple sclerosis (MS) have been much debated during
the past 50 years. It is now recognized that MS is a complex disease with different clinical …
the past 50 years. It is now recognized that MS is a complex disease with different clinical …
Pathogenic mechanisms associated with different clinical courses of multiple sclerosis
H Lassmann - Frontiers in immunology, 2019 - frontiersin.org
In the majority of patients multiple sclerosis starts with a relapsing remitting course (RRMS),
which may at later times transform into secondary progressive disease (SPMS). In a minority …
which may at later times transform into secondary progressive disease (SPMS). In a minority …
Multiple sclerosis: mechanisms and immunotherapy
C Baecher-Allan, BJ Kaskow, HL Weiner - Neuron, 2018 - cell.com
Multiple sclerosis (MS) is an autoimmune disease triggered by environmental factors that act
on a genetically susceptible host. It features three clinical stages: a pre-clinical stage …
on a genetically susceptible host. It features three clinical stages: a pre-clinical stage …