Multiple sclerosis (MS) is a multi‐component disease characterized by inflammation,
neurodegeneration and failure of central nervous system (CNS) repair mechanisms …

Two decades of clinical experience with immunomodulatory treatments for multiple sclerosis
point to distinct immunological pathways that drive disease relapses and progression. In …

This article provides a comprehensive overview of the pathology of multiple sclerosis (MS),
including recent insights into its molecular neuropathology and immunology. It shows that all …

Pathological examination of the affected human tissue is key to understanding the possible
mechanisms operating in the disease. In multiple sclerosis (MS), studies of central nervous …

Multiple sclerosis (MS) is an immune-mediated disease of the CNS that is characterized by
inflammation, demyelination, and axon loss. The inflammation in MS appears to be caused …

Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease
of the central nervous system of uncertain etiology. There is consensus that a dysregulated …

Multiple sclerosis (MS) is an inflammatory-mediated demyelinating disease of the human
central nervous system. The clinical disease course is variable, usually starts with reversible …

The etiology and pathogenesis of multiple sclerosis (MS) have been much debated during
the past 50 years. It is now recognized that MS is a complex disease with different clinical …

In the majority of patients multiple sclerosis starts with a relapsing remitting course (RRMS),
which may at later times transform into secondary progressive disease (SPMS). In a minority …

Multiple sclerosis (MS) is an autoimmune disease triggered by environmental factors that act
on a genetically susceptible host. It features three clinical stages: a pre-clinical stage …