The clinical and immunologic features of pulmonary fibrosis in sarcoidosis

KC Patterson, K Hogarth, AN Husain, AI Sperling… - Translational …, 2012 - Elsevier
Sarcoidosis is a multisystem, granulomatous disease that most often affects the lungs. The
clinical course is highly variable; many patients undergo spontaneous remission, but up to a …

From granuloma to fibrosis: sarcoidosis associated pulmonary fibrosis

CA Bonham, ME Strek… - Current opinion in …, 2016 - journals.lww.com
Understanding the mechanisms of fibrotic transformation in sarcoidosis enhances clinical
care and facilitates development of novel therapeutic options. The impact of these findings in …

Immune mechanisms in fibrotic pulmonary sarcoidosis

P Weeratunga, DR Moller, LP Ho - European Respiratory …, 2022 - Eur Respiratory Soc
Sarcoidosis is an immune-mediated disorder. Its immunopathology has been steadily
mapped out over the past few decades. Despite this, the underpinning mechanisms for …

Circulating cytokines in sarcoidosis: phenotype-specific alterations for fibrotic and non-fibrotic pulmonary disease

KC Patterson, BS Franek, J Müller-Quernheim… - Cytokine, 2013 - Elsevier
AIMS: Sarcoidosis is a granulomatous disease of unknown etiology marked by tremendous
clinical heterogeneity. Many patients enter remission with good long-term outcomes. Yet …

Sarcoidosis-associated pulmonary fibrosis: joining the dots

D Bandyopadhyay, MS Mirsaeidi - European Respiratory …, 2023 - Eur Respiratory Soc
Sarcoidosis is a multisystem granulomatous disorder of unknown aetiology. A minority of
patients with sarcoidosis develop sarcoidosis-associated pulmonary fibrosis (SAPF), which …

Inflammatory pathways in sarcoidosis

BP Barna, MA Judson, MJ Thomassen - … in Health and Disease, Volume II, 2021 - Springer
Abstract Concepts regarding etiology and pathophysiology of sarcoidosis have changed
remarkably within the past 5 years. Sarcoidosis is now viewed as a complex multi-causation …

The pathogenesis of pulmonary sarcoidosis and implications for treatment

KC Patterson, ES Chen - Chest, 2018 - Elsevier
Thoracic sarcoidosis is the most common form of sarcoidosis, encompassing a
heterogeneous group of patients with a wide range of clinical features and associated …

Pulmonary fibrosis in sarcoidosis. Clinical features and outcomes

KC Patterson, ME Strek - Annals of the American Thoracic Society, 2013 - atsjournals.org
Sarcoidosis is a systemic inflammatory disease with a predilection for the respiratory system.
Although most patients enter remission and have good long-term outcomes, up to 20 …

An expert overview of pulmonary fibrosis in sarcoidosis

R Gupta, JS Kim, RP Baughman - Expert Review of Respiratory …, 2023 - Taylor & Francis
Introduction Advanced pulmonary sarcoidosis refers to phenotypes of pulmonary
sarcoidosis that often lead to significant loss of lung function, respiratory failure, or death …

Strategies for identifying pulmonary sarcoidosis patients at risk for severe or chronic disease

MA Judson - Expert Review of Respiratory Medicine, 2017 - Taylor & Francis
Introduction: Most of the morbidity and mortality resulting from pulmonary sarcoidosis relates
to complications of fibrotic disease. Because the fibrosis related to pulmonary sarcoidosis is …