Advancements in the understanding of sarcoidosis support its consideration as an
autoimmune disease. Sarcoidosis patients carry a higher risk of comorbid autoimmune …

Idiopathic pulmonary fibrosis (IPF) and sarcoidosis are two distinct clinical entities with
different aetiology, epidemiology, risk factors, symptoms and chest imaging. A number of …

The widespread perception that sarcoidosis is essentially a benign disease has
undoubtedly contributed to a lack of investment in sarcoidosis-related public health and …

Sarcoidosis is characterized as a hyperimmune response to an unknown agent (s) at the
lesion sites. Regarding pulmonary lesions, macrophage-T lymphocyte alveolitis precedes …

Rationale: Sarcoidosis is known as a disease with high heterogeneity in clinical severity and
inflammatory activity. On the basis of radiologic criteria, John Guyette Scadding developed a …

Importance Sarcoidosis is an inflammatory granulomatous disease of unknown cause that
affects an estimated 2 to 160 people per 100 000 worldwide and can involve virtually any …

The aetiology of sarcoidosis is unclear. Single nucleotide polymorphisms (SNPs) in
transforming growth factor (TGF)-β2 and-β3 have been reported to be associated with the …

This is an update on sarcoidosis, focusing on etiology, diagnosis, and treatment. In the area
of etiopathogenesis, we now have a better understanding of the immune response that …

At the time of diagnosis, many sarcoidosis patients have no clinical indication for
corticosteroid therapy, and prognostic parameters predicting deterioration are missing. In the …

In granulomatous inflammatory lung diseases such as sarcoidosis, the balance of cytokine
production by activated T cells in the lungs may influence clinical disease outcome. To …