Distinct mechanisms of Drosophila CRYPTOCHROME-mediated light-evoked membrane depolarization and in vivo clock resetting

LS Baik, DD Au, C Nave, AJ Foden… - Proceedings of the …, 2019 - National Acad Sciences
Drosophila CRYPTOCHROME (dCRY) mediates electrophysiological depolarization and
circadian clock resetting in response to blue or ultraviolet (UV) light. These light-evoked …

CRYPTOCHROME-mediated phototransduction by modulation of the potassium ion channel β-subunit redox sensor

KJ Fogle, LS Baik, JH Houl, TT Tran… - Proceedings of the …, 2015 - National Acad Sciences
Blue light activation of the photoreceptor CRYPTOCHROME (CRY) evokes rapid
depolarization and increased action potential firing in a subset of circadian and arousal …

CRYPTOCHROME mediates behavioral executive choice in response to UV light

LS Baik, KJ Fogle, L Roberts… - Proceedings of the …, 2017 - National Acad Sciences
Drosophila melanogaster CRYPTOCHROME (CRY) mediates behavioral and
electrophysiological responses to blue light coded by circadian and arousal neurons …

Exquisite Light Sensitivity of Drosophila melanogaster Cryptochrome

P Vinayak, J Coupar, SE Hughes, P Fozdar… - PLoS …, 2013 - journals.plos.org
Drosophila melanogaster shows exquisite light sensitivity for modulation of circadian
functions in vivo, yet the activities of the Drosophila circadian photopigment cryptochrome …

Mechanism of Photosignaling by Drosophila Cryptochrome: ROLE OF THE REDOX STATUS OF THE FLAVIN CHROMOPHORE*♦

N Ozturk, CP Selby, D Zhong, A Sancar - Journal of Biological Chemistry, 2014 - ASBMB
Cryptochrome (CRY) is the primary circadian photoreceptor in Drosophila. Upon light
absorption, dCRY undergoes a conformational change that enables it to bind to Timeless …

An extraretinally expressed insect cryptochrome with similarity to the blue light photoreceptors of mammals and plants

ES Egan, TM Franklin… - Journal of …, 1999 - Soc Neuroscience
Photic entrainment of insect circadian rhythms can occur through either extraretinal (brain)
or retinal photoreceptors, which mediate sensitivity to blue light or longer wavelengths …

[HTML][HTML] Redox potential: differential roles in dCRY and mCRY1 functions

O Froy, DC Chang, SM Reppert - Current Biology, 2002 - cell.com
Cryptochromes (CRYs) are flavoproteins important for the molecular clocks of animals [1].
The Drosophila cryptochrome (dCRY) is a circadian photoreceptor [2–5], whereas mouse …

Linear motifs in the C-terminus of D. melanogaster cryptochrome

MJ Hemsley, GM Mazzotta, M Mason, S Dissel… - Biochemical and …, 2007 - Elsevier
The C-terminus of cryptochrome (CRY) regulates light responses in Drosophila. These
include the light-dependent binding of Drosophila dCRY to the clock proteins PERIOD and …

A constitutively active cryptochrome in Drosophila melanogaster

S Dissel, V Codd, R Fedic, KJ Garner, R Costa… - Nature …, 2004 - nature.com
Light-activated cryptochrome (CRY) regulates circadian photoresponses in Drosophila
melanogaster. Removing the carboxy (C) terminus to create CRYΔ produces, in yeast, a …

Reaction mechanism of Drosophila cryptochrome

N Ozturk, CP Selby, Y Annayev… - Proceedings of the …, 2011 - National Acad Sciences
Cryptochrome (CRY) is a blue-light sensitive flavoprotein that functions as the primary
circadian photoreceptor in Drosophila melanogaster. The mechanism by which it transmits …