Not as “D” eadly as once thought–the risk of D-alloimmunization and hemolytic disease of the fetus and newborn following RhD-positive transfusion in trauma

MH Yazer, G Panko, JB Holcomb, A Kaplan… - …, 2023 - Taylor & Francis
The use of blood products to resuscitate injured and massively bleeding patients in the
prehospital and early in-hospital phase of the resuscitation is increasing. Using group O red …

Use of low-titer O-positive whole blood in female trauma patients: a literature review, qualitative multidisciplinary analysis of risk/benefit, and guidelines for its use as a …

TW Clements, JM Van Gent, N Menon… - Journal of the …, 2023 - journals.lww.com
Background: Whole blood transfusion is associated with benefits including improved
survival, coagulopathy, and decreased transfusion requirements. The majority of whole …

Another piece of the hemolytic disease of the fetus and newborn puzzle after RhD-positive transfusion in trauma resuscitation: the proportion of pregnant women who …

MH Yazer, SP Emery, DJ Triulzi, P Spinella… - Trauma Surgery & …, 2024 - tsaco.bmj.com
Background After the transfusion of RhD-positive red blood cell (RBC)-containing products
to an RhD-negative woman of childbearing potential (WCP) during trauma resuscitation …

The risk to future pregnancies of transfusing Rh (D)‐negative females of childbearing potential with Rh (D)‐positive red blood cells during trauma resuscitation is …

JN Seheult, MN Stram, T Pearce, CB Bub… - Vox …, 2021 - Wiley Online Library
Background A risk assessment model for predicting the risk of haemolytic disease of the
fetus and newborn (HDFN) in future pregnancies following the transfusion of Rh (D)‐positive …

Estimating the risks of prehospital transfusion of D‐positive whole blood to trauma patients who are bleeding in England

R Cardigan, T Latham, A Weaver, M Yazer… - Vox …, 2022 - Wiley Online Library
Background and Objectives D‐negative red cells are transfused to D‐negative females of
childbearing potential (CBP) to prevent haemolytic disease of the foetus and newborn …

Rate of D‐alloimmunization in trauma does not depend on the number of RhD‐positive units transfused: the BEST collaborative study

JN Seheult, J Callum, M Delaney, R Drake… - …, 2022 - Wiley Online Library
Background Evidence indicates the life‐saving benefits of early blood product transfusion in
severe trauma resuscitation. Many of these products will be RhD‐positive, so understanding …

Anti-Rh alloimmunization after trauma resuscitation

LA Williams III, J Sikora, R Aldrees, HP Pham… - … and Apheresis Science, 2019 - Elsevier
The AABB recently posted a bulletin (19-02) regarding their recommendations for the use of
group O red blood cells (RBCs) during trauma. Though group O Rh (D)-negative RBC units …

Rate of RhD-alloimmunization after the transfusion of RhD-positive red blood cell containing products among injured patients of childbearing age: single center …

M Yazer, D Triulzi, J Sperry, A Corcos, J Seheult - Hematology, 2021 - Taylor & Francis
Objectives To determine the rate of RhD-alloimmunization in injured RhD-negative patients
in the age range of childbearing potential who were transfused with at least one unit of RhD …

Perception of risk in massive transfusion as it relates to fetal outcomes: a survey of surgeons and nurses at one American trauma center

R Uhlich, P Hu, M Yazer, JO Jansen, P Patrician… - …, 2021 - Wiley Online Library
Background The use of blood products early in the resuscitation of bleeding trauma patients
is widely accepted, but made difficult by limited supplies of D− red blood cell (RBC) …

Primum, non nocere: Whole blood, prehospital transfusion and anti‐D hemolytic disease of the fetus and newborn.

KL O'Brien, SA Shainker, J Callum, RH Chmait… - …, 2023 - search.ebscohost.com
However, it appears, when reviewing the available evidence and weighing risks and
benefits, patients of childbearing potential who are DNEG or when the RhD type is unknown …