[HTML][HTML] Glucosamine inhibits IL-1β-induced NFκB activation in human osteoarthritic chondrocytes

R Largo, MA Alvarez-Soria, I Dıez-Ortego… - Osteoarthritis and …, 2003 - Elsevier
Objective: Glucosamine sulfate (GS) is a commonly used drug for the treatment of
osteoarthritis. The mechanism of the action of this drug does, however, remain to be …

Glucosamine modulates IL‐1‐induced activation of rat chondrocytes at a receptor level, and by inhibiting the NF‐κB pathway

JN Gouze, A Bianchi, P Becuwe, M Dauca… - FEBS …, 2002 - Wiley Online Library
We recently reported that glucosamine reversed the decrease in proteoglycan synthesis and
in UDP‐glucuronosyltransferase I mRNA expression induced by interleukin‐1β (IL …

N-acetylglucosamine prevents IL-1β-mediated activation of human chondrocytes

AR Shikhman, K Kuhn, N Alaaeddine… - The Journal of …, 2001 - journals.aai.org
Glucosamine represents one of the most commonly used drugs to treat osteoarthritis.
However, mechanisms of its antiarthritic activities are still poorly understood. The present …

[HTML][HTML] Glucosamine sulfate reduces experimental osteoarthritis and nociception in rats: association with changes of mitogen-activated protein kinase in …

ZH Wen, CC Tang, YC Chang, SY Huang… - Osteoarthritis and …, 2010 - Elsevier
OBJECTIVE: To study the effects of oral glucosamine sulfate on the development of
osteoarthritis (OA) and to examine concomitant changes in the nociceptive behavior of rats …

[HTML][HTML] Glucosamine sulfate modulates dysregulated activities of human osteoarthritic chondrocytes in vitro

M Piperno, P Reboul, MPH Le Graverand… - Osteoarthritis and …, 2000 - Elsevier
Objective The efficacy of glucosamine sulfate (GS) in the symptomatic treatment of patients
with osteoarthritis (OA) is suggested to be mediated by still unknown effects on the altered …

Chondroitin Sulfate Inhibits the Nuclear Translocation of Nuclear Factor‐κB in Interleukin‐1β‐Stimulated Chondrocytes

C Jomphe, M Gabriac, TM Hale… - Basic & clinical …, 2008 - Wiley Online Library
Chondroitin sulfate is referred as a symptomatic slow‐acting drug for osteoarthritis because
it improves articular function, and reduces joint swelling and effusion. In addition, chondroitin …

[HTML][HTML] Exogenous glucosamine globally protects chondrocytes from the arthritogenic effects of IL-1β

JN Gouze, E Gouze, MP Popp, ML Bush… - Arthritis research & …, 2006 - Springer
The effects of exogenous glucosamine on the biology of articular chondrocytes were
determined by examining global transcription patterns under normal culture conditions and …

Epigallocatechin‐3‐gallate inhibits interleukin‐1β–induced expression of nitric oxide synthase and production of nitric oxide in human chondrocytes: suppression of …

R Singh, S Ahmed, N Islam, VM Goldberg… - Arthritis & …, 2002 - Wiley Online Library
Objective The proinflammatory cytokine interleukin‐1β (IL‐1β) induces the production of
high levels of nitric oxide (NO) in human chondrocytes. Green tea (Camellia sinensis) …

Preventive actions of a high dose of glucosamine on adjuvant arthritis in rats

J Hua, S Suguro, S Hirano, K Sakamoto… - Inflammation …, 2005 - Springer
Objective: Glucosamine, a naturally occurring amino monosaccharide has been used to
treat or prevent osteoarthritis in humans. In this study, we evaluated the effect of …

[HTML][HTML] Anti-inflammatory activity of monogalactosyldiacylglycerol in human articular cartilage in vitro: activation of an anti-inflammatory cyclooxygenase-2 (COX-2) …

V Ulivi, M Lenti, C Gentili, G Marcolongo… - Arthritis research & …, 2011 - Springer
Introduction The mono-and digalactosyldiacylglycerol (MGDG and DGDG) galactolipids
have been purified from the thermophilic blue-green alga Phormidium sp. ETS-05 that …