Our study aimed to investigate effect of tocilizumab on the lung tissue in the presence of
Acinetobacter baumannii infection in immunosuppressed rats. A forty-eight female Wistar …

Background/aim: Acute lung injury (ALI) is a major cause of death in the intensive care unit.
Lipopolysaccharide (LPS) induced lung injury is the most widely used experimental ALI …

Abstract Toll-like receptor 4 (TLR4) is involved in the regulation of host responses to
Acinetobacter baumannii (A. baumannii). The aim of the present study was to examine the …

Objective: In this study, the effect of tocilizumab (TCZ) on lung tissue in lung ischemia–
reperfusion (I/R) injury in rats was investigated. Material and Methods: A total of 24 Wistar …

Acinetobacter baumannii is the main causative pathogen of nosocomial infections that
causes severe infections in the lungs. In this study, we analyzed the histopathological …

Infection-related lipopolysaccharide (LPS) release causes cytokine storm and acute lung
injury. Emerging data show that the interleukin 6 (IL-6) inhibitor tocilizumab can improve …

Pulmonary drug delivery offers a minimally invasive and efficient method for treating lung
conditions, leveraging the lungs' extensive surface area and blood flow for rapid drug …

Background Acinetobacter baumannii (A. baumannii) has become one of the most important
opportunistic pathogens inducing nosocomial pneumonia and increasing mortality in …

Pulmonary drug delivery offers a minimally invasive and efficient method for treating lung
conditions, leveraging the lungs' extensive surface area and blood flow for rapid drug …

Objective To explore the effects of TLR4 on Acinetobacter baumannii (A. baumannii)
infection in a rat model. Methods Healthy male SD rats were divided into normal control …