The role of natural product chemistry in drug discovery
MS Butler - Journal of natural products, 2004 - ACS Publications
Although traditionally natural products have played an important role in drug discovery, in
the past few years most Big Pharma companies have either terminated or considerably …
the past few years most Big Pharma companies have either terminated or considerably …
Natural products as a foundation for drug discovery
JA Beutler - Current protocols in pharmacology, 2009 - Wiley Online Library
Natural products have provided chemical leads for the development of many drugs for
diverse indications. While most US pharmaceutical firms have reduced or eliminated their in …
diverse indications. While most US pharmaceutical firms have reduced or eliminated their in …
The value of natural products to future pharmaceutical discovery
DD Baker, M Chu, U Oza, V Rajgarhia - Natural product reports, 2007 - pubs.rsc.org
Covering: 2004 to 2006 Natural products have provided considerable value to the
pharmaceutical industry over the past half century. In particular, the therapeutic areas of …
pharmaceutical industry over the past half century. In particular, the therapeutic areas of …
Natural products as a foundation for drug discovery
JA Beutler - Current protocols in pharmacology, 2019 - Wiley Online Library
Many natural products have been used as drugs for the treatment of diverse indications.
Although most US pharmaceutical companies have reduced or eliminated their in‐house …
Although most US pharmaceutical companies have reduced or eliminated their in‐house …
Natural products in drug discovery: impacts and opportunities—an assessment
G Brahmachari - … natural products: opportunities and challenges in …, 2012 - World Scientific
Nature stands as an inexhaustible source of novel chemotypes and pharmacophores, and
has been a source of medicinal agents for thousands of years, and an impressive number of …
has been a source of medicinal agents for thousands of years, and an impressive number of …
The evolving role of natural products in drug discovery
FE Koehn, GT Carter - Nature reviews Drug discovery, 2005 - nature.com
Natural products and their derivatives have historically been invaluable as a source of
therapeutic agents. However, in the past decade, research into natural products in the …
therapeutic agents. However, in the past decade, research into natural products in the …
Natural products as a resource for new drugs
AM Clark - Pharmaceutical research, 1996 - Springer
Natural products have served as a major source of drugs for centuries, and about half of the
pharmaceuticals in use today are derived from natural products. The aim of this review is to …
pharmaceuticals in use today are derived from natural products. The aim of this review is to …
[图书][B] Natural product chemistry for drug discovery
AD Buss, MS Butler - 2010 - books.google.com
Page 1 RSC Biomolecular Sciences Edited by Antony D Buss and Mark S Butler Natural Product
Chemistry for Drug Discovery HOC HO 0= NH 0= HOC HN FO HN Q= HO₂C OH H₂NOC Fo …
Chemistry for Drug Discovery HOC HO 0= NH 0= HOC HN FO HN Q= HO₂C OH H₂NOC Fo …
Discovery, development, and regulation of natural products
Natural products have historically been an extremely productive source for new medicines in
all cultures and continue to deliver a great variety of structural templates for drug discovery …
all cultures and continue to deliver a great variety of structural templates for drug discovery …
Natural products in drug discovery–creating a new vision
GA Cordell - Phytochemistry Reviews, 2002 - Springer
Abstract “If only they had chosen to develop natural product drugs in a sustainable manner
at the turn of the century”. In 2050, when the Earth has a population of at least 9 billion, will …
at the turn of the century”. In 2050, when the Earth has a population of at least 9 billion, will …