Objective: Evolving evidence of anti-inflammatory effects is observed in patients with
rheumatoid arthritis or ulcerative colitis following periodic adsorptive granulocyte and …

Objective: Dramatic improvements in clinical symptoms of rheumatoid arthritis and ulcerative
colitis were observed after patients received granulocyte and monocyte adsorptive …

Granulocyte and monocyte adsorptive apheresis (GMA) using a column filled with cellulose
acetate (CA) beads (carriers) has been associated with a significant clinical efficacy in …

In active rheumatoid arthritis, large numbers of granulocytes and macrophages are found in
the inflamed joints. These leucocytes can promote inflammation and tissue injury by …

To elucidate the molecular mechanisms involved in the therapeutic effects of
granulocyte/monocyte adsorption apheresis, changes were investigated in the cytokine …

Our aim was to understand the mechanism of immunological changes associated with the
use of an adsorptive-type extracorporeal device (Adacolumn) that has been developed for …

We have studied the effects of granulocyte apheresis in 18 patients with ulcerative colitis
and 6 with Crohn's disease who had failed to respond to conventional therapy. Patients …

Recruitment of neutrophils into tissue occurs in several pathologic processes such as
inflammation, atherosclerosis, thrombosis, and ischemia. In inflammation, the adherence of …

BACKGROUND: Granulocyte and monocyte adsorptive apheresis (GMA) with an
Adacolumn has been reported to be effective as induction therapy in ulcerative colitis (UC) …

Serum hepatocyte growth factor (HGF) is rapidly increased in patients suffering from various
tissue injuries including arterial occlusive diseases. However, the cellular sources of the …