A double-blind, placebo-controlled clinical trial of fluoxetine in geriatric patients with major depression

GD Tollefson, JC Bosomworth… - International …, 1995 - cambridge.org
Depression in the geriatric population is a frequents, serious, and potentially reversible
disorder, yet relatively few blinded, controlled, antidepressant trial have been reported. A …

A double-blind study of paroxetine compared with fluoxetine in geriatric patients with major depression

W Schöne, M Ludwig - Journal of clinical psychopharmacology, 1993 - journals.lww.com
Abstract A 6-week, double-blind, parallel group study compared the efficacy and tolerability
of paroxetine and fluoxetine in 106 depressed geriatric outpatients (age,≥ 65 years) …

An overview of fluoxetine in geriatric depression

JP Feighner, WF Boyer, CH Meredith… - The British Journal of …, 1988 - cambridge.org
During the past 75 years, the proportion of elderly individuals in the USA has grown twice as
fast as the general population. Depression in this age-group occurs four times more …

Clinical response predictors in a double-blind, placebo-controlled trial of fluoxetine for geriatric major depression

GW Small, SH Hamilton, A Bystritsky… - International …, 1995 - cambridge.org
Background: We attempted to determine baseline characteristics predicting response in a 6-
week, double-blind, geriatric depression trial, which showed a significantly higher remission …

Fluoxetine: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in older patients with depressive illness

MG Harris, P Benfield - Drugs & Aging, 1995 - Springer
Synopsis The selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitor fluoxetine is
an effective antidepressant in elderly patients. Its efficacy is similar to that of other frequently …

Analysis of the Hamilton Depression Rating Scale factors from a double-blind, placebo-controlled trial of fluoxetine in geriatric major depression

GD Tollefson, SL Holman - International clinical …, 1993 - journals.lww.com
Major depression during later life represents a clinical challenge. Conventional
antidepressant pharmacotherapy is relatively less well tolerated in geriatric patients …

A double-blind, placebo-controlled study of venlafaxine and fluoxetine in geriatric outpatients with major depression

A Schatzberg, S Roose - The American journal of geriatric psychiatry, 2006 - Elsevier
Background Despite the high prevalence of depression in elderly patients, few well-
designed, placebo-controlled studies of antidepressants have been conducted in this …

Feasibility and effectiveness of treatments for depression in elderly medical inpatients: a systematic review

MG Cole, LM Elie, J McCusker… - International …, 2000 - cambridge.org
To determine the feasibility and effectiveness of treatments for depressed elderly medical
inpatients, MEDLINE was searched for potentially relevant articles published from January …

Paroxetine in the elderly depressed patient: randomized comparison with fluoxetine of efficacy, cognitive and behavioural effects

C Geretsegger, F Böhmer… - International clinical …, 1994 - journals.lww.com
The efficacy of paroxetine and fluoxetine and their effects on cognitive and behavioural
function were compared in a 6 week, double-blind, randomized study of 106 elderly …

Acute effects of fluoxetine versus placebo on functional health and well-being in late-life depression

JH Heiligenstein, JE Ware Jr, KM Beusterien… - International …, 1995 - cambridge.org
In a randomized 6-week trial comparing fluoxetine with placebo, the Medical Outcomes
Study 36-Item Short-Form Health Status Survey (SF-36) scales were used to measure the …