The role of secreted frizzled-related protein (SFRP) genes in gastric cancer remains largely
unknown. We determined the frequency and functional significance of SFRPs …

Hypermethylation of secreted frizzled‐related proteins (SFRP) genes frequently occurs with
several cancers but has not been studied in esophageal adenocarcinoma or its precursor …

AIM: To investigate the functions of promoter hyper-methylation of secreted frizzled-related
proteins (sFRPs) genes in colorectal tumorigenesis and progression. METHODS: The …

AIM: To identify the methylation of secreted frizzled-related protein 1 (SFRP1) in gastric
cancer and to investigate the aberrant expression of SFRP1 and its correlation with the …

Purpose The aim of this study was to investigate the diagnostic and prognostic significance
of the methylation status of secreted frizzled-related protein 2 (SFRP2) in colorectal cancer …

Expression of Secreted frizzled related protein 1 (SFRP1), a recently identified tumor
suppressor gene encoding a WNT signaling antagonist, has been found to be frequently …

BACKGROUND. The secreted frizzled‐related protein 1 gene (SFRP1) encodes a Wnt/β‐
catenin signaling antagonist and frequently is inactivated by promoter methylation in many …

Disruption of the Wnt pathway is thought to be crucial in the development of human cancer.
Pathway inhibitory members of the secreted frizzled-related protein (SFRP) family were …

AIM: To determine the methylation status and aberrant expression of some secreted frizzled-
related protein (SFRP) genes in pancreatic cancer and explore their role in pancreatic …

Secreted frizzled-related protein 1 (SFRP1) is a gene that belongs to the secreted
glycoprotein SFRP family. SFRP1 has been classified as a tumor suppressor gene due to …