Background: Clinical practice guidelines (CPGs) shape clinical care worldwide but are
prone to potential error and bias due to conflicts of interest (COI). Objective: To explore the …

Clinical practice guidelines are produced in ever-increasing numbers by the American
Academy of Neurology (AAN) and other developers, with over 1,000 guidelines currently in …

The American Academy of Neurology (AAN) has been a leader in developing clinical
practice guidelines. Both the Quality Standards Subcommittee (QSS) and the Therapeutics …

When there is sufficient evidence to support an inference for the use of an intervention (ie,
the balance of benefits and harms favors the intervention), the author panel assigns one of …

This manual has been created to provide instructions for developing an AAN clinical practice
guideline. AAN practice guidelines consist of a formalized review of the literature that serves …

When you pick up an issue of Neurology® and scan its contents, how do you decide what to
read? And how do you decide if what you read should change your clinical practice? The …

A neurologist is evaluating a patient in the office after the patient reported a 5-minute
episode of blindness of the right eye and clumsiness of the left arm. She orders a carotid …

Clinical guidelines are" statements that include recommendations, intended to optimize
patient care, that are informed by a systematic review of evidence and an assessment of the …

Level of evidence reviews: Three years of progress Page 1 Level of evidence reviews Three
years of progress Eric J. Ashman, MD Gary S. Gronseth, MD, FAAN Neurology® 2012;79:13–14 …

Background Clinical practice guidelines are systematically created documents that
summarize knowledge and assist in delivering high-quality medicine by identifying evidence …