A rapid, sensitive and specific method for the determination of cepharanthine in human
plasma using high performance liquid chromatography coupled with tandem mass …

A sensitive liquid chromatography–electrospray ionization–tandem mass spectrometry (LC–
ESI–MS–MS) method was developed and validated for the quantification of cepharanthine …

Context: Cepharanthine (CPA) has been reported to possess a wide range of
pharmacological activities. Objective: This study investigates the pharmacokinetic …

A rapid and simple procedure was developed for the determination of cephradine in human
plasma using liquid chromatography coupled with electrospray ionization-tandem mass …

Cepharanthine, a natural bisbenzylisoquinoline (BBIQ) alkaloid isolated from the plant
Stephania Cephalantha Hayata, is the only bisbenzylisoquinoline alkaloid approved for …

The pharmacokinetic disposition of Cepharanthin, a biscoclaurine alkaloid, was investigated
in healthy subjects following single intravenous doses of 25, 50, and 100mg and during and …

The spread of Plasmodium falciparum resistance toward most of the used drugs requires
new antimalarial compounds. Taking advantage of the biodiversity, the …

A sensitive and rapid LC–MS–MS method was developed for the simultaneous
determination of ebastine and carebastine in human plasma. Solid-phase extraction was …

The present work describes a reverse phase HPLC method for the quantitation of
drotaverine hydrochloride and mefenamic acid in human plasma. Organic solvent system …

Background Cepharanthine (CEP) is a drug used in Japan since the 1950s to treat a
number of acute and chronic diseases, including treatment of leukopenia, snake bites …