Novel xanthine and imidazolone derivatives were synthesized based on oxazolone
derivatives 2a-c as a key intermediate. The corresponding xanthine 3-5 and imidazolone …

Nucleoside analogs contribute in pharmaceutical and clinical fields as medicinal agents and
approved drugs. This work focused to investigate the antimicrobial, anticancer activities, and …

2-azido-1 H-benzo [d] imidazole derivatives 1a, b were reacted with a β-ketoester such as
acetylacetone in the presence of sodium ethoxide to obtain the desired molecules 2a, b. The …

A new series of pyridine-2-one and pyrazole derivatives were designed and synthesized
based on cyanoacrylamide derivatives containing 2, 4-dichlro aniline and 6-methyl 2-amino …

Antimicrobial resistance (AMR) and multidrug resistance (MDR) have become global
therapeutic barriers and due to this, there is increasing global mortality. To overcome …

Antibiotic and antifungal resistance problems have been prevalent in recent decades. One
of the efforts to solve the problems is to develop new medicines with more potent …

The recent study represented, the computational analysis, synthesis, characterization,
antimicrobial and molecular docking assessment of three compounds with some important …

Abstract Twenty compounds of pyrazolo [1, 5-a] pyrimidines 14a–j and pyrazole derivatives
as Schiff bases 16a–j have been synthesized by the reaction of 5-amino-pyrazole …

The present study aims to first explore the relationship between the chemical structure of the
organic compounds (pyridine based on 8-hydroxyquinoline) and the antibacterial activities …

In this study, a series of thiazolidine-2, 4-dione derivatives 3a–i were synthesized and
evaluated for antibacterial activity against Gram-positive and Gram-negative strains of …