The pharmacodynamics of piperacillin/tazobactam and cefepime were evaluated against
extended-spectrum β-lactamase (ESBL)-producing organisms. Ten thousand patients were …

Purpose The development and implementation of an extended-infusion piperacillin–
tazobactam program at an urban teaching hospital are described. Summary A …

The pharmacokinetic properties of piperacillin/tazobactam are summarized. The data on
piperacillin show that the behaviour of this well established agent is the same when given in …

The study objective was to evaluate the population pharmacokinetics and
pharmacodynamics of piperacillin and tazobactam administered by prolonged infusion in …

Evaluating the Appropriate Use of Piperacillin/Tazobactam in a Community Health System -
PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

Background Recently, continuous administration of piperacillin-tazobactam has been
proposed as a valuable alternative to traditional intermittent administration especially in …

The study objective was to evaluate steady-state pharmacokinetics and pharmacodynamics
of piperacillin and tazobactam administered by prolonged infusion in obese patients …

The clinical efficacy of continuous infusion of piperacillin/tazobactam in critically ill patients
with microbiologically documented infections is currently unknown. We conducted a …

Objective: To discuss the antimicrobial activity, pharmacokinetics, clinical efficacy, and
adverse effect profile of piperacillin/tazobactam, a new beta-lactam/beta-lactamase inhibitor …

Abstract Ceftolozane/tazobactam (CTZ/TZ) exhibits time-dependent antimicrobial activity,
and prolonged infusion can better achieve the pharmacodynamic target than an intermittent …