The relevance of-amino-butyric acid (GABA)-ergic dysfunctions in the pathology of
Alzheimer's disease (AD) remains a matter of debate. In the present study, we characterized …

Our work on the role of glutamate in Alzheimer's disease (AD)-related neuronal vulnerability
and death provided significant insight into the potential contribution of the γ-aminobutyric …

In AD, it is hypothesized that one factor contributing to the vulnerability of neurons is a
delicate balance of excitatory and inhibitory inputs. To examine this hypothesis we have …

GABA (gamma-aminobutyric acid) receptor modulators have been investigated as a
potential treatment strategy in Alzheimer's disease (AD). In the present study, we found that …

Alzheimer's disease (AD) is a complex and chronic neurodegenerative disorder that
involves a progressive and severe decline in cognition and memory. During the last few …

Alzheimer's disease (AD) is the most common form of dementia that is often accompanied by
mood and emotional disturbances and seizures. There is growing body of evidence that …

Beta‐amyloid (A β) accumulation, neuroinflammation, basal forebrain cholinergic loss and
hippocampal degeneration are well‐described pathologies associated with A lzheimer's …

A characteristic feature of neuritic plaques in Alzheimer's disease is represented by the
presence of activated astrocytes, surrounding dystrophic neurons and β-amyloid deposition …

β-Amyloid is the primary protein component of neuritic plaques, which are degenerative foci
in brains of patients with Alzheimer's disease (AD). The effects of this naturally occurring β …

Neurodegeneration in Alzheimer's disease is characterized by a selective loss of particular
cell populations. Several recent lines of evidence suggest thatβ-amyloid protein directly …