A cross-species analysis of the cystic fibrosis transmembrane conductance regulator. Potential functional domains and regulatory sites.
G Diamond, TF Scanlin, MA Zasloff… - Journal of Biological …, 1991 - ASBMB
To help elucidate the function of the cystic fibrosis transmembrane conductance regulator
(CFTR), we have undertaken a cross-species analysis of the DNA sequence which encodes …
(CFTR), we have undertaken a cross-species analysis of the DNA sequence which encodes …
Comparative genomic sequence analysis of the human and mouse cystic fibrosis transmembrane conductance regulator genes
RE Ellsworth, DC Jamison… - Proceedings of the …, 2000 - National Acad Sciences
The identification of the cystic fibrosis transmembrane conductance regulator gene (CFTR)
in 1989 represents a landmark accomplishment in human genetics. Since that time, there …
in 1989 represents a landmark accomplishment in human genetics. Since that time, there …
Cloning the mouse homolog of the human cystic fibrosis transmembrane conductance regulator gene
The cystic fibrosis transmembrane conductance regulator is encoded by the gene known to
be mutated in patients with cystic fibrosis. This paper reports the cloning and sequencing of …
be mutated in patients with cystic fibrosis. This paper reports the cloning and sequencing of …
Immunocytochemical analysis reveals differences between the subcellular localization of normal and ΔPhe508 recombinant cystic fibrosis transmembrane …
W Dalemans, J Hinnrasky, P Slos, D Dreyer… - Experimental cell …, 1992 - Elsevier
Cystic fibrosis (CF) is caused by mutations in the gene coding for the cystic fibrosis
transmembrane conductance regulator (CFTR). The most common mutation responsible for …
transmembrane conductance regulator (CFTR). The most common mutation responsible for …
Multiple mutations in highly conserved residues are found in mildly affected cystic fibrosis patients
M Dean, MB White, J Amos, B Gerrard, C Stewart… - Cell, 1990 - cell.com
We have identified three different point mutations in the coding region of the cystic fibrosis
transmembrane conductance regulator (CFTR) gene. Each mutation segregates with the …
transmembrane conductance regulator (CFTR) gene. Each mutation segregates with the …
[HTML][HTML] Alternative splicing of intron 23 of the human cystic fibrosis transmembrane conductance regulator gene resulting in a novel exon and transcript coding for a …
K Yoshimura, CS Chu, RG Crystal - Journal of Biological Chemistry, 1993 - Elsevier
The cystic fibrosis transmembrane conductance regulator (CFTR) gene, the gene
responsible for the lethal hereditary disorder cystic fibrosis, codes for a membrane protein …
responsible for the lethal hereditary disorder cystic fibrosis, codes for a membrane protein …
Expression and chromosome localization of the murine cystic fibrosis transmembrane conductance regulator
KA Kelley, S Stamm, CA Kozak - Genomics, 1992 - Elsevier
Abstract A 13.5-kb genomic fragment of the mouse cystic fibrosis transmembrane
conductance regulator (CFTR) gene was isolated from a C 57 BL 6 J liver DNA library, using …
conductance regulator (CFTR) gene was isolated from a C 57 BL 6 J liver DNA library, using …
[HTML][HTML] Partial purification of the cystic fibrosis transmembrane conductance regulator.
LS Ostedgaard, MJ Welsh - Journal of Biological Chemistry, 1992 - Elsevier
We have investigated several purification strategies for the cystic fibrosis transmembrane
regulator (CFTR) based on its structural similarity to other proteins of the traffic ATPase/ABC …
regulator (CFTR) based on its structural similarity to other proteins of the traffic ATPase/ABC …
[HTML][HTML] Characterization of the promoter region of the cystic fibrosis transmembrane conductance regulator gene.
JL Chou, R Rozmahel, LC Tsui - Journal of Biological Chemistry, 1991 - Elsevier
To identify the transcription regulatory elements of the cystic fibrosis transmembrane
conductance regulator (CFTR) gene, DNA fragments located in the 5 '-upstream region were …
conductance regulator (CFTR) gene, DNA fragments located in the 5 '-upstream region were …
Molecular cloning and sequence analysis of the murine cDNA for the cystic fibrosis transmembrane conductance regulator
T Yorifuji, WK Lemna, CF Ballard, CL Rosenbloom… - Genomics, 1991 - Elsevier
We have cloned the mouse homolog of the human cystic fibrosis transmembrane
conductance regulator (CFTR) using clones isolated from a mouse lung cDNA library and …
conductance regulator (CFTR) using clones isolated from a mouse lung cDNA library and …