Ligand-targeted liposome design: challenges and fundamental considerations

GT Noble, JF Stefanick, JD Ashley, T Kiziltepe… - Trends in …, 2014 - cell.com
Nanomedicine, particularly liposomal drug delivery, has expanded considerably over the
past few decades, and several liposomal drugs are already providing improved clinical …

Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: Challenges and opportunities

L Belfiore, DN Saunders, M Ranson… - Journal of controlled …, 2018 - Elsevier
The development of therapeutic resistance to targeted anticancer therapies remains a
significant clinical problem, with intratumoral heterogeneity playing a key role. In this context …

Ligand-targeted liposomes

E Forssen, M Willis - Advanced drug delivery reviews, 1998 - Elsevier
Liposomes have gained increased attention as systemic drug delivery vehicles following
recent regulatory approvals of several vesicle-formulated drugs. These products have …

Current trends in the use of liposomes for tumor targeting

PP Deshpande, S Biswas, VP Torchilin - Nanomedicine, 2013 - Taylor & Francis
The use of liposomes for drug delivery began early in the history of pharmaceutical
nanocarriers. These nanosized, lipid bilayered vesicles have become popular as drug …

Ligation strategies for targeting liposomal nanocarriers

P Marqués-Gallego… - BioMed research …, 2014 - Wiley Online Library
Liposomes have been exploited for pharmaceutical purposes, including diagnostic imaging
and drug and gene delivery. The versatility of liposomes as drug carriers has been …

[HTML][HTML] Liposomes for tumor targeted therapy: a review

S Wang, Y Chen, J Guo, Q Huang - International journal of molecular …, 2023 - mdpi.com
Liposomes, the most widely studied nano-drug carriers in drug delivery, are sphere-shaped
vesicles consisting of one or more phospholipid bilayers. Compared with traditional drug …

Ligand-targeted liposomes.

M Willis, E Forssen - Advanced Drug Delivery Reviews, 1998 - europepmc.org
Liposomes have gained increased attention as systemic drug delivery vehicles following
recent regulatory approvals of several vesicle-formulated drugs. These products have …

Liposomal delivery systems: design optimization and current applications

ASA Lila, T Ishida - Biological and pharmaceutical bulletin, 2017 - jstage.jst.go.jp
The liposome, a closed phospholipid bilayered vesicular system, has received considerable
attention as a pharmaceutical carrier of great potential over the past 30 years. The ability of …

Advances in tumor targeted liposomes

A Jain, SK Jain - Current molecular medicine, 2018 - ingentaconnect.com
Cancer remains a deadly disease for effective treatment. Although anomalous tumor
microenvironment is now widely exploited for targeted chemotherapy, safe and efficacious …

Ligand-targeted liposomal anticancer drugs

P Sapra, TM Allen - Progress in lipid research, 2003 - Elsevier
Antibody or ligand-mediated targeting of liposomal anticancer drugs to antigens expressed
selectively or over-expressed on tumor cells is increasingly being recognized as an effective …