Dysregulated Expression Patterns of Circular RNAs in Cancer: Uncovering Molecular Mechanisms and Biomarker Potential

NR DeSouza, KJ Nielsen, T Jarboe, M Carnazza… - Biomolecules, 2024 - mdpi.com
Circular RNAs (circRNAs) are stable, enclosed, non-coding RNA molecules with dynamic
regulatory propensity. Their biogenesis involves a back-splicing process, forming a highly …

[HTML][HTML] The progress of circular RNAs in various tumors

D Wang, S Yang, H Wang, J Wang… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs), a novel type of non-coding RNAs, presented as covalently closed
continuous loops. Recent researches had found that circRNAs could function as microRNA …

Circular RNAs (circRNAs) in cancer

R Zhou, Y Wu, W Wang, W Su, Y Liu, Y Wang, C Fan… - Cancer letters, 2018 - Elsevier
Circular RNAs (circRNAs) are a class of non-coding RNAs that do not have 5′ end caps or
3′ end poly (A) tails. There are more than one hundred thousand genes that encode …

[HTML][HTML] A Circular RNAs: Emerging roles and new insights in human cancers

Z He, Q Zhu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Circular RNAs (circRNAs) are single-stranded, covalently closed RNA molecules formed by
mRNA exon back-splicing. Although the circRNA functions remain largely unknown, their …

[HTML][HTML] Circular RNAs in cancer: limitations in functional studies and diagnostic potential

F Li, Q Yang, AT He, BB Yang - Seminars in cancer biology, 2021 - Elsevier
Circular RNAs (circRNAs) are a large class of noncoding RNAs, generated from a process
called back-splicing, that possess critical regulatory functions in many cellular events. A …

Role of circular RNAs in disease progression and diagnosis of cancers: An overview of recent advanced insights

SU Khan, MU Khan, MI Khan, AA Fadahunsi… - International journal of …, 2022 - Elsevier
Tumor microenvironment (TME) is a crucial regulator of tumor progression and cells in the
TME release a number of molecules that are responsible for anaplasticity, invasion …

Biological roles and mechanisms of circular RNA in human cancers

Q Tang, SS Hann - OncoTargets and therapy, 2020 - Taylor & Francis
Circular RNA (circRNA) is an intriguing class of RNA with covalently closed-loop structure
and is highly stable and conservative. As new members of the ncRNAs, the function …

Circles reshaping the RNA world: from waste to treasure

J Liu, T Liu, X Wang, A He - Molecular cancer, 2017 - Springer
A new type of RNAs was identified from genes traditionally thought to express messenger or
linear ncRNA (noncoding RNA) only. They were subsequently named as circRNAs (circular …

The emerging role of circRNAs and their clinical significance in human cancers

L Qian, S Yu, Z Chen, Z Meng, S Huang… - Biochimica et Biophysica …, 2018 - Elsevier
Circular RNA (circRNA), a recently discovered subclass of non-coding RNAs (ncRNAs),
forms a covalently closed loop with neither a 5′ cap structure nor a 3′ polyadenylated tail …

The regulatory functions of circular RNAs in digestive system cancers

X Yuan, Y Yuan, Z He, D Li, B Zeng, Q Ni, M Yang… - Cancers, 2020 - mdpi.com
Circular ribonucleic acids (circRNAs), which are a type of covalently closed circular RNA,
are receiving increasing attention. An increasing amount of evidence suggests that …