Polycystic ovary syndrome (PCOS) is the leading cause of infertility in reproductive-age
women. Hyperandrogenism, polycystic ovaries, and chronic anovulation are its typical …

Background Epigenetic reprogramming is involved in luteinizing hormone (LH)-induced
ovulation; however, the underlying mechanisms are largely unknown. Results We here …

Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disease in women
of reproductive age. Ovarian dysfunction including abnormal steroid hormone synthesis and …

Background Women with polycystic ovary syndrome (PCOS) manifest a host of ovarian
defects like impaired folliculogenesis, anovulation, and poor oocyte quality, which grossly …

Background/Aim: Theca cells produce androgen by 17α-hydroxylase-17, 20-lyase encoded
by Cyp17a1, and conversion of androgen to estrogen in granulosa cells is regulated by …

Abstract Histone deacetylase 1 (HDAC1) is known to participate in the molecular etiology of
polycystic ovary syndrome (PCOS). However, its role in granulosa cell (GC) pyroptosis …

Background Although hormonal and metabolic dysfunction have been recognized as a
possible cause of polycystic ovarian syndrome (PCOS), the associations between …

Abstract Polycystic Ovary Syndrome (PCOS) is the most common endocrine disorder
amongst women of reproductive age, whose aetiology remains unclear. To improve our …

As one of the most common endocrine disorders affecting women, polycystic ovary
syndrome (PCOS) is associated with serious conditions including anovulation, endometrial …

Polycystic ovary syndrome (PCOS) is the most common complex endocrine and metabolic
disease in women of reproductive age. It is characterized by anovulatory infertility, hormone …