Recent knowledge on the pathophysiology of septic acute kidney injury: a narrative review
Sepsis is the commonest cause of acute kidney injury in critically ill patients. Its
pathophysiology is complex and not well understood. Until recently, it was believed that …
pathophysiology is complex and not well understood. Until recently, it was believed that …
A unified theory of sepsis-induced acute kidney injury: inflammation, microcirculatory dysfunction, bioenergetics, and the tubular cell adaptation to injury
H Gomez, C Ince, D De Backer, P Pickkers, D Payen… - Shock, 2014 - journals.lww.com
Given that the leading clinical conditions associated with acute kidney injury (AKI), namely,
sepsis, major surgery, heart failure, and hypovolemia, are all associated with shock, it is …
sepsis, major surgery, heart failure, and hypovolemia, are all associated with shock, it is …
Sepsis-associated AKI: epithelial cell dysfunction
Acute kidney injury (AKI) occurs frequently in critically ill patients with sepsis, in whom it
doubles the mortality rate and half of the survivors suffer permanent kidney damage or …
doubles the mortality rate and half of the survivors suffer permanent kidney damage or …
Sepsis-induced acute kidney injury revisited: pathophysiology, prevention and future therapies
An understanding of the pathologic mechanisms of sepsis-induced AKI emphasizes the
important role of maladaptive responses to the septic insult. Preventive and therapeutic …
important role of maladaptive responses to the septic insult. Preventive and therapeutic …
Sepsis-associated acute kidney injury
CL Manrique-Caballero… - Critical Care …, 2021 - criticalcare.theclinics.com
Sepsis-associated acute kidney injury (S-AKI) is a common, life-threatening complication in
hospitalized and critically ill patients. S-AKI increases in-hospital mortality 6-fold to 8-fold, 1 …
hospitalized and critically ill patients. S-AKI increases in-hospital mortality 6-fold to 8-fold, 1 …
[HTML][HTML] Renal perfusion in sepsis: from macro-to microcirculation
The pathogenesis of sepsis-associated acute kidney injury is complex and likely involves
perfusion alterations, a dysregulated inflammatory response, and bioenergetic …
perfusion alterations, a dysregulated inflammatory response, and bioenergetic …
[HTML][HTML] Acute kidney injury from sepsis: current concepts, epidemiology, pathophysiology, prevention and treatment
S Peerapornratana, CL Manrique-Caballero… - Kidney international, 2019 - Elsevier
Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …
Cellular pathophysiology of ischemic acute kidney injury
JV Bonventre, L Yang - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Ischemic kidney injury often occurs in the context of multiple organ failure and sepsis. Here,
we review the major components of this dynamic process, which involves hemodynamic …
we review the major components of this dynamic process, which involves hemodynamic …
Recent advances in pathophysiology and biomarkers of sepsis-induced acute kidney injury
Sepsis is a complex clinical syndrome characterized by a systemic inflammatory response to
an infective insult. This process often leads to widespread tissue injury and multiple organ …
an infective insult. This process often leads to widespread tissue injury and multiple organ …