Sepsis is considered a major public health problem. Despite mortality being associated
consistently with organ compromise, the mechanisms by which sepsis causes multiple …

Sepsis is the commonest cause of acute kidney injury in critically ill patients. Its
pathophysiology is complex and not well understood. Until recently, it was believed that …

Given that the leading clinical conditions associated with acute kidney injury (AKI), namely,
sepsis, major surgery, heart failure, and hypovolemia, are all associated with shock, it is …

Acute kidney injury (AKI) occurs frequently in critically ill patients with sepsis, in whom it
doubles the mortality rate and half of the survivors suffer permanent kidney damage or …

An understanding of the pathologic mechanisms of sepsis-induced AKI emphasizes the
important role of maladaptive responses to the septic insult. Preventive and therapeutic …

Sepsis-associated acute kidney injury (S-AKI) is a common, life-threatening complication in
hospitalized and critically ill patients. S-AKI increases in-hospital mortality 6-fold to 8-fold, 1 …

The pathogenesis of sepsis-associated acute kidney injury is complex and likely involves
perfusion alterations, a dysregulated inflammatory response, and bioenergetic …

Sepsis-associated acute kidney injury (S-AKI) is a frequent complication of the critically ill
patient and is associated with unacceptable morbidity and mortality. Prevention of S-AKI is …

Ischemic kidney injury often occurs in the context of multiple organ failure and sepsis. Here,
we review the major components of this dynamic process, which involves hemodynamic …

Sepsis is a complex clinical syndrome characterized by a systemic inflammatory response to
an infective insult. This process often leads to widespread tissue injury and multiple organ …