Mitochondria: the indispensable players in innate immunity and guardians of the inflammatory response

A Mohanty, R Tiwari-Pandey, NR Pandey - Journal of cell communication …, 2019 - Springer
Mitochondria, the dynamic organelles and power house of eukaryotic cells function as
metabolic hubs of cells undergoing continuous cycles of fusion and fission. Recent findings …

Mitochondrial control of innate immunity and inflammation

HS Jin, HW Suh, SJ Kim, EK Jo - Immune Network, 2017 - synapse.koreamed.org
Mitochondria are key organelles involved in energy production, functioning as the metabolic
hubs of cells. Recent findings emphasize the emerging role of the mitochondrion as a key …

Mitochondria, oxidative stress and innate immunity

Y Chen, Z Zhou, W Min - Frontiers in physiology, 2018 - frontiersin.org
Canonical functions of mitochondria include the regulation of cellular survival, orchestration
of anabolic and metabolic pathways, as well as reactive oxygen species (ROS) signaling …

Mitochondria in the regulation of innate and adaptive immunity

SE Weinberg, LA Sena, NS Chandel - Immunity, 2015 - cell.com
Mitochondria are well appreciated for their role as biosynthetic and bioenergetic organelles.
In the past two decades, mitochondria have emerged as signaling organelles that contribute …

Mitochondria: sensors and mediators of innate immune receptor signaling

SM Cloonan, AMK Choi - Current opinion in microbiology, 2013 - Elsevier
Highlights•Mitochondrial fission/fusion and mitophagy regulators modulate RLR
responses.•NLRP3 activation is dependent on mitochondrial localization and mROS.•Cyclic …

Mitochondria in innate immune signaling

B Banoth, SL Cassel - Translational Research, 2018 - Elsevier
Mitochondria are functionally versatile organelles. In addition to their conventional role of
meeting the cell's energy requirements, mitochondria also actively regulate innate immune …

Mitochondrial control of innate immune responses

S Chen, Z Liao, P Xu - Frontiers in immunology, 2023 - frontiersin.org
Mitochondria are versatile organelles and essential components of numerous biological
processes such as energy metabolism, signal transduction, and cell fate determination. In …

Mitochondria in innate immune responses

AP West, GS Shadel, S Ghosh - Nature Reviews Immunology, 2011 - nature.com
The innate immune system has a key role in the mammalian immune response. Recent
research has demonstrated that mitochondria participate in a broad range of innate immune …

Metabolism and innate immunity meet at the mitochondria

A Bahat, T MacVicar, T Langer - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Mitochondria are master regulators of metabolism and have emerged as key signalling
organelles of the innate immune system. Each mitochondrion harbours potent agonists of …

[HTML][HTML] Mitochondria as a centrally positioned hub in the innate immune response

R Sandhir, A Halder, A Sunkaria - … Acta (BBA)-Molecular Basis of Disease, 2017 - Elsevier
Mitochondria are vital organelles involved in numerous cellular functions ranging from
energy metabolism to cell survival. Emerging evidence suggests that mitochondria provide a …