Liquid–liquid phase separation (LLPS) of proteins containing intrinsically disordered regions
(IDRs) has been proposed as a mechanism underlying the formation of membrane-less …

Mechanisms driving the prolonged meiotic prophase I in mammals are poorly understood.
RNA helicase YTHDC2 is critical for mitosis to meiosis transition. However, YTHDC2 is …

DDX3 (or Ded1p), the highly conserved subfamily of the DEAD-box RNA helicase family (40
members in humans), plays important roles in RNA metabolism. DDX3X and DDX3Y, the …

DDX3 belongs to the DEAD box family of RNA helicases, but the details of its biological
function remain largely unclear. Here we show that knockdown of DDX3 expression …

Lysine-specific histone demethylase 1 (LSD1) is an essential epigenetic regulator in
metazoans and requires the co-r epressor e lement-1 s ilencing t ranscription factor …

Although it is apparent that chromosome complement mediates sexually dimorphic
expression patterns of some proteins that lead to functional differences, there has been …

DEAD-box RNA helicases play various, often critical, roles in all processes where RNAs are
involved. Members of this family of proteins are linked to human disease, including cancer …

Asp-Glu-Ala-Asp (DEAD)-box polypeptide 5 (DDX5), also called p68, is a prototypical
member of the large ATP-dependent RNA helicases family and is known to participate in all …

As one of the most abundant modifications on mRNA in mammal, N6-methyladenosine
(m6A) has been demonstrated to play important roles in various biological processes …

Phase separation of biological molecules, such as nucleic acids and proteins, has garnered
widespread attention across many fields in recent years. For instance, liquid-liquid phase …