Update on inflammatory biomarkers and treatments in ischemic stroke

A Bonaventura, L Liberale, A Vecchié… - International journal of …, 2016 - mdpi.com
After an acute ischemic stroke (AIS), inflammatory processes are able to concomitantly
induce both beneficial and detrimental effects. In this narrative review, we updated evidence …

Anti-inflammatory targets for the treatment of reperfusion injury in stroke

A Mizuma, MA Yenari - Frontiers in neurology, 2017 - frontiersin.org
While the mainstay of acute stroke treatment includes revascularization via recombinant
tissue plasminogen activator or mechanical thrombectomy, only a minority of stroke patients …

[HTML][HTML] Neuroinflammatory biomarkers: from stroke diagnosis and prognosis to therapy

A Simats, T García-Berrocoso, J Montaner - Biochimica et Biophysica Acta …, 2016 - Elsevier
Stroke is the third leading cause of death in industrialized countries and one of the largest
causes of permanent disability worldwide. Therapeutic options to fight stroke are still limited …

Inflammatory molecules might become both biomarkers and therapeutic targets for stroke management

L Ramiro, A Simats… - Therapeutic …, 2018 - journals.sagepub.com
Stroke is the fifth leading cause of death and the most frequent cause of disability worldwide.
Currently, stroke diagnosis is based on neuroimaging; therefore, the lack of a rapid tool to …

[HTML][HTML] Cytokines: their role in stroke and potential use as biomarkers and therapeutic targets

DN Doll, TL Barr, JW Simpkins - Aging and disease, 2014 - ncbi.nlm.nih.gov
Inflammatory mechanisms both in the periphery and in the CNS are important in the
pathophysiologic processes occurring after the onset of ischemic stroke (IS). Cytokines are …

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

SE Lakhan, A Kirchgessner, M Hofer - Journal of translational medicine, 2009 - Springer
Acute ischemic stroke is the third leading cause of death in industrialized countries and the
most frequent cause of permanent disability in adults worldwide. Despite advances in the …

Post-stroke inflammation—target or tool for therapy?

KL Lambertsen, B Finsen, BH Clausen - Acta neuropathologica, 2019 - Springer
Inflammation is currently considered a prime target for the development of new stroke
therapies. In the acute phase of ischemic stroke, microglia are activated and then circulating …

Role of inflammation and its mediators in acute ischemic stroke

R Jin, L Liu, S Zhang, A Nanda, G Li - Journal of cardiovascular …, 2013 - Springer
Inflammation plays an important role in the pathogenesis of ischemic stroke and other forms
of ischemic brain injury. Increasing evidence suggests that inflammatory response is a …

Inflammatory biomarkers of ischemic stroke

A Tirandi, C Sgura, F Carbone, F Montecucco… - Internal and emergency …, 2023 - Springer
Ischemic stroke remains the second leading cause of death and among the major causes of
morbidity worldwide. Therapeutic options are currently limited to early reperfusion strategies …

Inflammatory responses after ischemic stroke

JH DeLong, SN Ohashi, KC O'Connor… - Seminars in …, 2022 - Springer
Ischemic stroke generates an immune response that contributes to neuronal loss as well as
tissue repair. This is a complex process involving a range of cell types and effector …