Background Introduction of antiretroviral therapy (ART) in sub-Saharan Africa was a hot
debate due to many concerns about adherence, logistics and resistance. Currently, it has …

Background The ongoing scale-up of antiretroviral therapy (ART) in sub-Saharan Africa has
prompted the interest in surveillance of transmitted and acquired HIV drug resistance …

Background The emergence, accumulation and spread of HIV-1 drug resistance strains in
Africa could compromise the effectiveness of HIV treatment programs. This study was aimed …

Background: High rates of disease progression and HIV drug resistance (HIVDR) among
adults taking highly active antiretroviral treatment (HAART) in Sub-Saharan Africa were …

Background Antiretroviral treatment has played a pivotal role in the reduction of HIV/AIDS-
related morbidity and mortality. However, treatment options can be impaired by the …

The emergence of HIV-1 drug resistance mutations has mainly been linked to the duration
and composition of antiretroviral treatment (ART), as well as the level of adherence. This …

Background Antiretroviral therapy (ART) regimen failure is linked to an increased risk of
disease progression and death, while early detection of ART failure can help to prevent the …

Background: Since the advent of HAART, there is a significant reduction in opportunistic
Infections (OIs), morbidity, mortality and HIV transmission. However, the low antiretroviral …

Introduction The current expansion of antiretroviral treatment (ART) in the developing world
without routine virological monitoring still raises concerns on the outcome of the strategy in …

Background Virological response to antiretroviral treatment (ART) in rural Africa is poorly
described. We examined virological efficacy and emergence of drug resistance in adults …