Validation of the particle-based multi-analyte technology for detection of anti-phosphatidylserine/prothrombin antibodies

M Radin, I Cecchi, SG Foddai, E Rubini, A Barinotti… - Biomedicines, 2020 - mdpi.com
Among “extra-criteria” antiphospholipid (aPL) antibodies, anti-phosphatidylserine/
prothrombin (aPS/PT) antibodies, are considered a part of risk assessment strategies when …

Comparative assessment of the diagnostic performances of particle-based multianalyte technology and commercial ELISA for antiphospholipid autoantibody testing

A Saadalla, CL Novis, D Banerjee, T Martins… - Clinica Chimica …, 2024 - Elsevier
Abstract Background: Diagnosing Antiphospholipid Syndrome (APS) relies heavily on
laboratory findings, particularly the detection of specific antibodies like lupus anticoagulant …

[PDF][PDF] Improving the clinical accuracy in patients with antiphospholipid antibodies using anti-phosphatidylserine/prothrombin and anti-beta2 glycoprotein I domain and …

M Radin, S Foddai, I Cecchi, E Rubini, A Barinotti… - Thrombosis …, 2021 - iris.unito.it
Antiphospholipid syndrome (APS) is the most common acquired thrombophilia, an
autoimmune disorder characterized by arterial and/or venous thrombosis and/or pregnancy …

Comparative analysis of different enzyme immunoassays for assessment of phosphatidylserine-dependent antiprothrombin antibodies

O Amengual, T Horita, W Binder, GL Norman… - Rheumatology …, 2014 - Springer
Phosphatidylserine-dependent antiprothrombin antibodies (aPS/PT) were strongly
correlated with the presence of lupus anticoagulant showing a high specificity for the …

Evaluation of novel assays for the detection of autoantibodies in antiphospholipid syndrome

S Sciascia, M Radin, C Ramirez, A Seaman… - Autoimmunity …, 2020 - Elsevier
Patients with antiphospholipid syndrome (APS) present with clinical features of recurrent
thrombosis and pregnancy morbidity and persistently test positive for the presence of …

Laboratory testing for non-criteria antiphospholipid antibodies: anti-phosphatidylserine/prothrombin antibodies (aPS/PT)

KMJ Devreese - Hemostasis and Thrombosis: Methods and Protocols, 2023 - Springer
Since the discovery that antiphospholipid antibodies (aPL) bind to a cofactor at the
phospholipid membrane, the proteins beta-2-glycoprotein I (β2GPI) and prothrombin …

Evaluation of the sensitivity and specificity of a novel line immunoassay for the detection of criteria and non-criteria antiphospholipid antibodies in comparison to …

MA Thaler, A Bietenbeck, U Steigerwald, T Büttner… - PLoS …, 2019 - journals.plos.org
Background Persistent antiphospholipid antibodies (aPL) constitute the serological hallmark
of the antiphospholipid syndrome (APS). Recently, various new assay technologies for the …

The introduction of anti-phosphatidylserine/prothrombin autoantibodies in the laboratory diagnostic process of anti-phospholipid antibody syndrome: 6 months of …

M Fabris, R Giacomello, A Poz, L Pantarotto… - Autoimmunity …, 2014 - Springer
Purpose To evaluate the impact of the introduction of the anti-phosphatidylserine/
prothrombin autoantibodies (aPS/PT) in the laboratory diagnostic process of anti …

Criteria and Non-Criteria Antiphospholipid Antibodies in Antiphospholipid Syndrome: How Strong Are They Correlated?

S Caraiola, L Voicu, C Jurcut, A Dima, C Baicus… - Biomedicines, 2023 - mdpi.com
The place of non-criteria antiphospholipid antibodies (aPLs) in the diagnosis of
antiphospholipid syndrome (APS) is still debatable. The aim of this research was to evaluate …

Antiphospholipid antibody profiling—time for a new technical approach?

D Roggenbuck, K Egerer, P von Landenberg… - Autoimmunity …, 2012 - Elsevier
Detection of anti-phospholipid (aPL) antibodies for state-of-the art diagnosis of
antiphospholipid syndrome (APS) still remains a laboratory challenge due to the great …