T-cell regulation in helminth parasite infections: implications for inflammatory diseases

R Maizels, M Yazdanbakhsh - T Cell Regulation in Allergy, Asthma and …, 2008 - karger.com
The field of infectious disease immunology is at an exciting intersection with new concepts in
immune regulation meeting with the dynamics of infectious diseases. We discuss how the …

Helminth infections and host immune regulation

HJ McSorley, RM Maizels - Clinical microbiology reviews, 2012 - Am Soc Microbiol
Helminth parasites infect almost one-third of the world's population, primarily in tropical
regions. However, regions where helminth parasites are endemic record much lower …

Regulation of allergy and autoimmunity in helminth infection

MS Wilson, RM Maizels - Clinical reviews in allergy & immunology, 2004 - Springer
Parasitic infections are a major theme in the “hygiene hypothesis”, as allergies and
autoimmune diseases are less prevalent in countries with higher burdens of helminths and …

Helminth parasites–masters of regulation

RM Maizels, A Balic, N Gomez‐Escobar… - Immunological …, 2004 - Wiley Online Library
Immune regulation by parasites is a global concept that includes suppression, diversion,
and conversion of the host immune response to the benefit of the pathogen. While many …

Regulation of pathogenesis and immunity in helminth infections

RM Maizels, EJ Pearce, D Artis… - Journal of Experimental …, 2009 - rupress.org
Helminths are multicellular eukaryotic parasites that infect over one quarter of the world's
population. Through coevolution with the human immune system, these organisms have …

Chronic helminth infections induce immunomodulation: consequences and mechanisms

E van Riet, FC Hartgers, M Yazdanbakhsh - Immunobiology, 2007 - Elsevier
Worldwide, more than a billion people are infected with helminths. These worm infections
generally do not lead to mortality, however, they are chronic in nature and can lead to …

Immune responses to helminth infection

S Babu, TB Nutman - Clinical Immunology, 2019 - Elsevier
Over 2 billion people worldwide are infected with helminths (worms). Helminth infections are
a major public health problem worldwide due to their ability to cause significant morbidity …

Exploring the immunology of parasitism–from surface antigens to the hygiene hypothesis

RM Maizels - Parasitology, 2009 - cambridge.org
Helminth immunology is a field which has changed beyond recognition in the past 30 years,
transformed not only by new technologies from cDNA cloning to flow cytometry, but also …

[HTML][HTML] Helminth parasites and immune regulation

PH Gazzinelli-Guimaraes, TB Nutman - F1000Research, 2018 - ncbi.nlm.nih.gov
Helminth parasites are complex metazoans that belong to different taxonomic families but
that collectively share the capacity to downregulate the host immune response directed …

[HTML][HTML] Regulation of the host immune system by helminth parasites

RM Maizels, HJ McSorley - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
Helminth parasite infections are associated with a battery of immunomodulatory
mechanisms that affect all facets of the host immune response to ensure their persistence …