Innate immune receptors: key regulators of metabolic disease progression

C Jin, J Henao-Mejia, RA Flavell - Cell metabolism, 2013 - cell.com
The study of the intersection of immunology and metabolism is a growing field fueled by the
increased prevalence of obesity-associated pathologies. Importantly, the capacity of the …

The role of the immune system in metabolic health and disease

N Zmora, S Bashiardes, M Levy, E Elinav - Cell metabolism, 2017 - cell.com
In addition to the immune system's traditional roles of conferring anti-infectious and anti-
neoplastic protection, it has been recently implicated in the regulation of systemic metabolic …

[HTML][HTML] Immunometabolism: where immunology and metabolism meet

T Chavakis - Journal of Innate Immunity, 2022 - karger.com
In the last two decades,“Immunometabolism” has emerged as a continuously increasing
area of research with significant impact on biomedicine [1, 2]. The term immunometabolism …

Foundations of immunometabolism and implications for metabolic health and disease

GS Hotamisligil - Immunity, 2017 - cell.com
Highly ordered interactions between immune and metabolic responses are evolutionarily
conserved and paramount for tissue and organismal health. Disruption of these interactions …

Emerging concepts in intestinal immune control of obesity-related metabolic disease

S Khan, H Luck, S Winer, DA Winer - Nature Communications, 2021 - nature.com
The intestinal immune system is an important modulator of glucose homeostasis and obesity-
associated insulin resistance. Dietary factors, the intestinal microbiota and their metabolites …

Feeding our immune system: impact on metabolism

I Wolowczuk, C Verwaerde, O Viltart… - Journal of …, 2008 - Wiley Online Library
Endogenous intestinal microflora and environmental factors, such as diet, play a central role
in immune homeostasis and reactivity. In addition, microflora and diet both influence body …

Innate immune activation in obesity

CN Lumeng - Molecular aspects of medicine, 2013 - Elsevier
The innate immune system is a prewired set of cellular and humoral components that has
developed to sense perturbations in normal physiology and trigger responses to restore the …

Regulation of systemic metabolism by tissue-resident immune cell circuits

JH Li, MR Hepworth, TE O'Sullivan - Immunity, 2023 - cell.com
Recent studies have demonstrated that tissue homeostasis and metabolic function are
dependent on distinct tissue-resident immune cells that form functional cell circuits with …

Immune regulation of metabolic homeostasis in health and disease

JR Brestoff, D Artis - Cell, 2015 - cell.com
Obesity is an increasingly prevalent disease worldwide. While genetic and environmental
factors are known to regulate the development of obesity and associated metabolic …

The intestinal immune system in obesity and insulin resistance

DA Winer, H Luck, S Tsai, S Winer - Cell metabolism, 2016 - cell.com
Obesity and insulin resistance are associated with chronic inflammation in metabolic tissues
such as adipose tissue and the liver. Recently, growing evidence has implicated the …