Recent studies have suggested that lymphatics help to restore heart function after cardiac
injury,,,,–. Here we report that lymphatics promote cardiac growth, repair and …

The lymphatic vasculature is a blind-ended network crucial for tissue-fluid homeostasis,
immune surveillance and lipid absorption from the gut. Recent evidence has proposed an …

Myocardial infarction (MI) arising from obstruction of the coronary circulation engenders
massive cardiomyocyte loss and replacement by non-contractile scar tissue, leading to …

Background Lymphatic vessels interconnect with blood vessels to form an elaborate system
that aids in the control of tissue pressure and edema formation. Although the lymphatic …

Background: The adherens protein VE-cadherin (vascular endothelial cadherin) has diverse
roles in organ-specific lymphatic vessels. However, its physiological role in cardiac …

The lymphatic network of mammalian heart is an important regulator of interstitial fluid
compartment and immune cell trafficking. We observed a remodeling of the cardiac …

In recent years, there has been increasing interest in the role of lymphatics in organ repair
and regeneration, due to their importance in immune surveillance and fluid homeostasis …

Objective: Lymphatics play an essential pathophysiological role in promoting fluid and
immune cell tissue clearance. Conversely, immune cells may influence lymphatic function …

The lineage and developmental trajectory of a cell are key determinants of cellular identity.
In the vascular system, endothelial cells (ECs) of blood and lymphatic vessels differentiate …

The lymphatic vasculature has an essential role in maintaining normal fluid balance in
tissues and modulating the inflammatory response to injury or pathogens. Disruption of …