Embryonic expression of a haematopoietic growth factor encoded by the SI locus and the ligand for c-kit
MICE carrying mutations at the W (Dominant white spotting) and SI (Steel) loci develop
abnormalities in three independent systems: neural crest-derived melanocytes, primordial …
abnormalities in three independent systems: neural crest-derived melanocytes, primordial …
Embryonic RNA expression patterns of the c‐kit receptor and its cognate ligand suggest multiple functional roles in mouse development.
E Keshet, SD Lyman, DE Williams, DM Anderson… - The EMBO …, 1991 - embopress.org
Mutations at the dominant white spotting (W) and Steel (Sl) loci in mouse exert deleterious
effects on three migratory cell lineages (primordial germ cells, melanocytes and …
effects on three migratory cell lineages (primordial germ cells, melanocytes and …
Reversible expansion of primate mast cell populations in vivo by stem cell factor.
SJ Galli, A Iemura, DS Garlick… - The Journal of …, 1993 - Am Soc Clin Investig
Mast cell development in mice is critically regulated by stem cell factor (SCF), the term used
here to designate a product of fibroblasts and other cell types that is a ligand for the tyrosine …
here to designate a product of fibroblasts and other cell types that is a ligand for the tyrosine …
SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain
M Kozlowski, L Larose, F Lee, DM Le… - … and cellular biology, 1998 - Am Soc Microbiol
The SH2 domain-containing SHP-1 tyrosine phosphatase has been shown to negatively
regulate a broad spectrum of growth factor-and cytokine-driven mitogenic signaling …
regulate a broad spectrum of growth factor-and cytokine-driven mitogenic signaling …
Primary structure of c‐kit: relationship with the CSF‐1/PDGF receptor kinase family–oncogenic activation of v‐kit involves deletion of extracellular domain and C …
FH Qiu, P Ray, K Brown, PE Barker, S Jhanwar… - The EMBO …, 1988 - embopress.org
The protein kinase domains of v‐kit, the oncogene of the acute transforming feline retrovirus
HZ4‐FeSV (HZ4‐feline sarcoma virus), CSF‐1R (macrophage colony stimulating factor …
HZ4‐FeSV (HZ4‐feline sarcoma virus), CSF‐1R (macrophage colony stimulating factor …
Further phenotypic characterization and isolation of human hematopoietic progenitor cells using a monoclonal antibody to the c-kit receptor
RA Briddell, VC Broudy, E Bruno, JE Brandt, EF Srour… - 1992 - ashpublications.org
A mouse antihuman monoclonal IgG2a antibody, termed stem cell receptor-1 (SR-1),
specific for a determinant of the c-kit ligand receptor (KR), was used as an immunologic …
specific for a determinant of the c-kit ligand receptor (KR), was used as an immunologic …
The kit ligand encoded at the murine Steel locus: a pleiotropic growth and differentiation factor
P Besmer - Current opinion in cell biology, 1991 - Elsevier
The c-kit receptor and its recently identified ligand are allelic with the murine White Spotting
and Steel loci, respectively. These observations brought to light the functions of the c-kit …
and Steel loci, respectively. These observations brought to light the functions of the c-kit …
Mechanism of kit ligand, phorbol ester, and calcium-induced down-regulation of c-kit receptors in mast cells
NS Yee, H Langen, P Besmer - Journal of Biological Chemistry, 1993 - ASBMB
The proto-oncogene c-kit is allelic with the white spotting locus (W) on mouse chromosome
5 and it encodes a transmembrane protein tyrosine kinase which belongs to the platelet …
5 and it encodes a transmembrane protein tyrosine kinase which belongs to the platelet …