SCARs are rare and life-threatening hypersensitivity reactions. In general, the increased
duration of hospital stays and the associated cost burden are common issues, and in the …

Most immune-mediated adverse drug reactions (IM-ADRs) involve the skin, and many have
additional systemic features. Severe cutaneous adverse drug reactions (SCARs) are an …

Severe cutaneous adverse reactions (SCARs) such as Stevens-Johnson syndrome, toxic
epidermal necrolysis (SJS/TEN), and drug reaction with eosinophilia and systemic …

Severe cutaneous adverse reactions (SCARs), previously thought to be idiosyncratic or
unpredictable, are a deadly form of adverse drug reactions with skin manifestations. Current …

Severe cutaneous adverse reactions (SCARs) encompass a heterogeneous group of
delayed hypersensitivity reactions, which are most frequently caused by drugs. Our …

Human leukocyte antigen (HLA) encoded by the HLA gene is an important modulator for
immune responses and drug hypersensitivity reactions as well. Genetic polymorphisms of …

Severe cutaneous adverse reactions (SCARs), which include Stevens–Johnson syndrome
and toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (also …

Introduction: Pharmacogenomics has great potential in reducing drug-induced severe
cutaneous adverse drug reactions (SCARs). Pharmacogenomic studies have revealed an …

Adverse drug reactions (ADRs) affect many patients and remain a major public health
problem, as they are a common cause of morbidity and mortality. It is estimated that ADRs …

Abstract Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug
reaction with eosinophilia and systemic symptoms (DRESS) are severe cutaneous adverse …