Cells lacking the Dictyostelium 34,000-D actin-bundling protein, a calcium-regulated actin
cross-linking protein, were created to probe the function of this polypeptide in living cells …

The interaction with actin and intracellular localization of the 30,000-D actin-binding protein
from the cellular slime mold Dictyostelium discoideum have been investigated to analyze the …

Actin-binding proteins are known to regulate in vitro the assembly of actin into
supramolecular structures, but evidence for their activities in living nonmuscle cells is …

In many nonmuscle cells, actin filaments are located underneath the plasma membrane in a
region called the cortex. During cell locomotion a reorganization of the cortex is expected to …

The cell cortex of Dictyostelium amebae contains an actin-rich cytoplasmic matrix. Changes
in geometry of this matrix are believed to regulate protrusive activity and motility of the cell …

We have studied the abundance, relative gelation activity, and distribution of the 95,000-
dalton actin-binding protein in Dictyostelium discoideum amoebae. The 95,000-dalton …

Dictyostelium discoideum contains a soluble actin‐binding protein that caps actin filaments
at their fast growing ends. The purified protein consists of two subunits with 34 kd and 32 kd …

A calcium-sensitive actin-binding protein having a subunit molecular mass of 30,000 daltons
(30K protein) has been isolated from Dictyostelium discoideum. Structural, immunological …

We have studied the effect of the Dictyostelium discoideum 30,000-D actin-bundling protein
on the assembly and disassembly of pyrenyl-labeled actin in vitro. The results indicate that …

Dictyostelium is a suitable experimental system in which to study the effects of mutations in
actin-binding proteins on cell motility. Three cytoskeletal mutants that show distinct …