Background Thymic stromal lymphopoietin (TSLP) is a major proallergic cytokine that
promotes TH 2 responses through dendritic cell (DC) activation. Whether it also plays a role …

Atopic dermatitis results in diminished barrier function and altered production of
antimicrobial peptides. Dendritic epidermal T cells (DETCs) play an important role in the …

Background Innate immune sensors control key cytokines that regulate T-cell priming and T-
cell fate. This is particularly evident in allergic reactions, which represent ideal systems to …

To the Editor: Atopic dermatitis (AD) is a pruritic and inflammatory skin disorder
characterized by barrier disruption. The cytokine thymic stromal lymphopoietin (TSLP), a …

Atopic dermatitis (AD) is one of the most common inflammatory skin diseases with complex
pathogenesis involving epidermal barrier dysfunction, skin microbiome abnormalities and …

Atopic dermatitis often precedes the development of asthma, a phenomenon known as
“atopic march”. An important role of allergen sensitization developed through barrier …

In the skin lesions of atopic dermatitis (AD), keratinocytes release large quantities of thymic
stromal lymphopoietin (TSLP), causing unfavorable inflammation along with skin damage …

Atopic dermatitis (AD) is an inflammatory disease driven in part by type 2 helper T (Th2)
cytokines and skin barrier disruption alleviating the entry of allergens. Thymic stromal …

The cytokine thymic stromal lymphopoietin (TSLP) has been implicated in the initiation and
progression of allergic inflammation through its ability to activate dendritic cells (DCs) …

Background Atopic dermatitis (AD) is one of the most common skin diseases with a
multifactorial etiology. Mutations leading to loss of skin barrier function are associated with …