BACKGROUND: Atopic dermatitis is characterized by scratching and by TH2-dominated
immune response to cutaneously introduced antigens. Antigen application to skin …

Type 2 inflammation underlies allergic diseases such as atopic dermatitis, which is
characterized by the accumulation of basophils and group 2 innate lymphoid cells (ILC2s) in …

Although atopic dermatitis (AD) is the initial step of the “atopic march”, a progression from
AD to asthma, the underlying mechanism remains unknown. Selective expression of IL-13 in …

Atopic dermatitis is a common, chronic inflammatory skin disease that is characterized by
skin barrier dysfunction, inflammation and intense itch. Although the exact mechanisms …

Psoriasis is a common inflammatory skin disease involving a cross‐talk between epidermal
and immune cells. The role of specific epidermal stem cell populations, including hair follicle …

Background Atopic dermatitis (AD) is a chronic inflammatory skin disease that often cannot
be completely controlled by modern medicine. Since multiple factors are intricately involved …

Despite its presence on resident skin cells, the role of TLR4 in skin diseases remains poorly
understood. This is highly significant because the skin biome is rich with potential TLR4 …

Type 2 immunity, illustrated by T helper 2 lymphocytes (Th2) and downstream cytokines (IL-
4, IL-13, IL-31) as well as group 2 innate lymphoid cells (ILC2), is important in host defense …

Atopic dermatitis (AD) is an inflammatory skin disease characterized by skin barrier
dysfunction. Although T helper type 2 cytokines downregulate the expression of epidermal …

Atopic dermatitis (AD), a skin disease characterized by pruritus and chronic inflammation,
results from a complex interplay between environmental and genetic factors. Thymic stromal …