Quinoline heterocycles have been considered important structures due to their diverse
applications in organic synthesis, coordination chemistry, as well as in the fields of drug …

Background: Along with the progress in medicine and therapies, the exploitation of anti-
cancer agents focused more on the vital signaling pathways and key biological …

Cancer is one of the most difficult diseases and causes of death for many decades. Many
pieces of research are continuously going on to get a solution for cancer. Quinoline and …

Quinoline and its analogues are found in various natural products, many of which are active
pharmacophores with significant bioactivities. This article discussed the plethora of …

Quinoline (1-azanaphthalene) is a heterocyclic aromatic nitrogen compound characterized
by a double-ring structure that contains a benzene ring fused to pyridine at two adjacent …

Among heterocyclic compounds, quinoline scaffold has become an important construction
motif for the development of new drugs. Quinoline and its derivatives possess many types of …

A series of new quinoline derivatives was designed, synthesized and evaluated for their
antiproliferative activity. The results demonstrated that compounds 11p, 11s, 11v, 11x and …

Background: On account of significant biological activities, quinoline derivatives have drawn
more attention to the synthesis and biological activities in the search for new therapeutic …

Introduction: The concept of privileged structures is well known and is often used in the
process of drug design and development. Although its assumptions are not clear, its overall …

Tetrahydroquinoline and isoquinoline scaffolds are important class of heterocyclic
compounds, which is implied for the development of new drugs and diagnostic for …