Background Prostate cancer (PCa) is one of the most common cancers and the fifth leading
cause of cancer-related death in men. Immune responses in the tumor microenvironment …

Immune microenvironment of prostate cancer (PCa) is implicated in disease progression.
However, previous studies have not fully explored PCa immune microenvironment. This …

Background The tumor microenvironment (TME) has recently been proven to play a crucial
role in the development and prognosis of tumors. However, the current knowledge on the …

Background The tumor microenvironment (TME) primarily comprises cancer cells, cancer-
infiltrating immune cells, and stromal cells. The tumor cells alter the TME by secreting …

Background An increasing number of studies has indicated that the tumor microenvironment
(TME), an important component of tumor tissue, has clinicopathological significance in …

Androgen deprivation therapy (ADT) is a cornerstone treatment for locally advanced or
metastatic prostate cancer (PCa). However, its potential effects on the tumor immune …

Prostate cancer (PCa) is the fifth leading cause of death from cancer in men worldwide. Its
treatment remains challenging due to the heterogeneity of the tumor, mainly because of the …

Background Prostate cancer (PCa) is an immune-responsive disease. The current study
sought to explore a robust immune-related prognostic gene signature for PCa. Methods …

The tumor immune microenvironment (TIME) consists of multiple cell types that contribute to
the heterogeneity and complexity of prostate cancer (PCa). In this study, we sought to …

Background: Immunotherapy has a significant effect on the treatment of many tumor types.
However, prostate cancers generally fail to show significant responses to immunotherapy …