A systematic review highlights threats to validity in studies of barriers to cancer trial participation

D Fayter, C McDaid, A Eastwood - Journal of clinical epidemiology, 2007 - Elsevier
OBJECTIVE: To investigate the barriers, modifiers, and benefits involved in participating in
randomized controlled trials of cancer therapies as perceived by health care providers and …

[HTML][HTML] Systematic review of barriers, modifiers and benefits involved in participation in cancer clinical trials

D Fayter, C McDaid, G Ritchie, L Stirk, A Eastwood - 2006 - eprints.whiterose.ac.uk
AIM Our aim was to undertake a systematic review of the relevant literature relating to the
barriers, modifiers and benefits involved in participating in randomised controlled trials of …

Systematic review and meta-analysis of the magnitude of structural, clinical, and physician and patient barriers to cancer clinical trial participation

JM Unger, R Vaidya, DL Hershman… - JNCI: Journal of the …, 2019 - academic.oup.com
Background Barriers to cancer clinical trial participation have been the subject of frequent
study, but the rate of trial participation has not changed substantially over time. Studies often …

Why patients don't take part in cancer clinical trials: an overview of the literature

K Cox, J McGarry - European journal of cancer care, 2003 - Wiley Online Library
Why patients don't take part in cancer clinical trials: an overview of the literature Clinical
trials have been recognized extensively within the literature as a crucial component in the …

Barriers to clinical trial participation as perceived by oncologists and patients

NJ Meropol, JS Buzaglo, J Millard, N Damjanov… - Journal of the National …, 2007 - jnccn.org
Although clinical trial research is required for the development of improved treatment
strategies, very few cancer patients participate in these studies. The purpose of this study …

[HTML][HTML] Role of clinical trial participation in cancer research: barriers, evidence, and strategies

JM Unger, E Cook, E Tai, A Bleyer - American Society of Clinical …, 2016 - ncbi.nlm.nih.gov
Fewer than 1 in 20 adult cancer patients enroll in cancer clinical trials. But although barriers
to trial participation have been the subject of frequent study, the rate of trial participation has …

Survival Benefit Associated With Participation in Clinical Trials of Anticancer Drugs: A Systematic Review and Meta-analysis

R Iskander, H Moyer, K Vigneault, SM Mahmud… - JAMA, 2024 - jamanetwork.com
Importance Many cancer clinical investigators view clinical trials as offering better care for
patients than routine clinical care. However, definitive evidence of clinical benefit from trial …

Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors

EJ Mills, D Seely, B Rachlis, L Griffith, P Wu… - The lancet …, 2006 - thelancet.com
Background Enrolling participants onto clinical trials of cancer presents an important
challenge. We aimed to identify the concerns of patients with cancer about, and the barriers …

Assessment of perceived cost to the patient and other barriers to clinical trial participation

DJ Weckstein, CA Thomas, IF Emery… - Journal of Oncology …, 2011 - ascopubs.org
Purpose: Less than 5% of patients with cancer participate in trials. Few studies have
specifically addressed the role of cost to the patient as an influence on trial participation. Our …

“When offered to participate”: a systematic review and meta-analysis of patient agreement to participate in cancer clinical trials

JM Unger, DL Hershman, C Till… - JNCI: Journal of the …, 2021 - academic.oup.com
Background Patient participation in clinical trials is vital for knowledge advancement and
outcomes improvement. Few adult cancer patients participate in trials. Although patient …