Antitumor activity of gold (III)‐dithiocarbamato derivatives on prostate cancer cells and xenografts
L Cattaruzza, D Fregona, M Mongiat… - … journal of cancer, 2011 - Wiley Online Library
Among the nonplatinum antitumor drugs, gold (III)‐dithiocarbamato derivatives have recently
attracted considerable attention due to their strong in vitro and in vivo antiproliferative activity …
attracted considerable attention due to their strong in vitro and in vivo antiproliferative activity …
[HTML][HTML] Potent in vitro and in vivo anticancer activity of new bipyridine and bipyrimidine gold (III) dithiocarbamate derivatives
We synthesized eight new bipyridine and bipyrimidine gold (III) dithiocarbamate-containing
complexes (C1–C8) and tested them in a panel of human cancer cell lines. We used …
complexes (C1–C8) and tested them in a panel of human cancer cell lines. We used …
Gold dithiocarbamate derivatives as potential antineoplastic agents: design, spectroscopic properties, and in vitro antitumor activity
L Ronconi, L Giovagnini, C Marzano, F Bettìo… - Inorganic …, 2005 - ACS Publications
At present, cisplatin (cis-diamminodichloroplatinum (II)) is one of the most largely employed
anticancer drugs as it is effective in the treatment of 70− 90% of testicular and, in …
anticancer drugs as it is effective in the treatment of 70− 90% of testicular and, in …
Gold (III)‐dithiocarbamato anticancer agents: Activity, toxicology and histopathological studies in rodents
C Marzano, L Ronconi, F Chiara… - … journal of cancer, 2011 - Wiley Online Library
Gold (III)‐dithiocarbamato complexes have recently gained increasing attention as potential
anticancer agents because of their strong tumor cell growth–inhibitory effects, generally …
anticancer agents because of their strong tumor cell growth–inhibitory effects, generally …
[HTML][HTML] New bipyridine gold (III) dithiocarbamate-containing complexes exerted a potent anticancer activity against cisplatin-resistant cancer cells independent of p53 …
We synthesized, characterized and tested in a panel of cancer cell lines, nine new bipyridine
gold (III) dithiocarbamate-containing complexes. In vitro studies demonstrated that …
gold (III) dithiocarbamate-containing complexes. In vitro studies demonstrated that …
[PDF][PDF] Gold (III)-dithiocarbamato complexes induce cancer cell death triggered by thioredoxin redox system inhibition and activation of ERK pathway
D Saggioro, MP Rigobello, L Paloschi, A Folda… - Chemistry & biology, 2007 - cell.com
Although gold compounds are now recognized as promising anticancer agents, so far only
gold (I) derivatives have been investigated for this purpose, whereas the use of gold (III) …
gold (I) derivatives have been investigated for this purpose, whereas the use of gold (III) …
Latest insights into the anticancer activity of gold (III)-dithiocarbamato complexes
L Ronconi, D Aldinucci, Q Ping Dou… - Anti-Cancer Agents in …, 2010 - ingentaconnect.com
In this review paper we aim at giving a detailed overview on our research work devoted to
the design of gold-based anticancer agents. In particular, during the last decade, we have …
the design of gold-based anticancer agents. In particular, during the last decade, we have …
New selective thiolate gold (i) complexes inhibit the proliferation of different human cancer cells and induce apoptosis in primary cultures of mouse colon tumors
E Abas, R Pena-Martinez, D Aguirre-Ramírez… - Dalton …, 2020 - pubs.rsc.org
New thiolate gold (I) complexes with P (NMe2) 3 (HMPT) as a phosphane group [Au
(SR)(HMPT)](SR= Spy, Spyrim, SMe2pyrim, Sbenzothiazole, Sthiazoline, Sbenzimidazole …
(SR)(HMPT)](SR= Spy, Spyrim, SMe2pyrim, Sbenzothiazole, Sthiazoline, Sbenzimidazole …
Proteasome versus thioredoxin reductase competition as possible biological targets in antitumor mixed thiolate-dithiocarbamate gold (III) complexes
J Quero, S Cabello, T Fuertes, I Mármol… - Inorganic …, 2018 - ACS Publications
New mixed gold (III) derivatives with dithiocarbamate and thiolate ligands have been
synthesized and characterized. They display high anticancer activity against colon cancer …
synthesized and characterized. They display high anticancer activity against colon cancer …
Antiproliferative and apoptotic effects of two new gold (III) methylsarcosinedithiocarbamate derivatives on human acute myeloid leukemia cells in vitro
D Aldinucci, D Lorenzon, L Stefani, L Giovagnini… - Anti-cancer …, 2007 - journals.lww.com
Abstract [Au (MSDT) Cl 2](dichloro [methyl N-(dithiocarboxy-kS, kS′)-N-methylglicinato]
gold (III)) and [Au (MSDT) Br 2](dibromo [methyl N-(dithiocarboxy-kS, kS′)-N …
gold (III)) and [Au (MSDT) Br 2](dibromo [methyl N-(dithiocarboxy-kS, kS′)-N …
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