Aspergillus fumigatus is an opportunistic mould that causes invasive pulmonary
aspergillosis (IPA), a life‐threatening infection in immunocompromised patients. During the …

Infection by the human fungal pathogen Aspergillus fumigatus induces hypoxic
microenvironments within the lung that can alter the course of fungal pathogenesis. How …

The mold Aspergillus fumigatus causes life-threatening infections in immunocompromised
patients. Over the past decade, new findings in research have improved our understanding …

Humans are continuously exposed to airborne spores of the saprophytic fungus Aspergillus
fumigatus. However, in healthy individuals pulmonary host defense mechanisms efficiently …

In order to cause disease, all pathogens must tolerate microenvironmental stresses
encountered in vivo during infection. One microenvironmental stress that is known to occur …

Hypoxia as a result of pulmonary tissue damage due to unresolved inflammation during
invasive pulmonary aspergillosis (IPA) is associated with a poor outcome. Aspergillus …

In immunocompromised patients, invasive aspergillosis (IA) is the most frequent disease
caused by the pathogenic mould Aspergillus fumigatus. Fever is one of the most common …

Lung immunity and susceptibility to infections is subject to interactions between the
epithelial layer and immune cells residing in the pulmonary space. Aspergillus (A.) …

Aspergillus fumigatus is the most frequent causative agent of invasive aspergillosis, a
predominant life-threatening opportunistic infection in immunocompromised individuals. A …

Recent estimates suggest that more than 3 million people have chronic or invasive fungal
infections, causing more than 600,000 deaths every year. Aspergillus fumigatus causes …