Long-term moderate oxidative stress decreased ovarian reproductive function by reducing follicle quality and progesterone production

L Shi, J Zhang, Z Lai, Y Tian, L Fang, M Wu, J Xiong… - PloS one, 2016 - journals.plos.org
Ovarian aging is a long-term and complex process associated with a decrease in follicular
quantity and quality. The damaging effects of reactive oxygen species (ROS) in ovarian …

Premature ovarian insufficiency: a review on the role of oxidative stress and the application of antioxidants

YQ Shi, XT Zhu, SN Zhang, YF Ma, YH Han… - Frontiers in …, 2023 - frontiersin.org
Normal levels of reactive oxygen species (ROS) play an important role in regulating follicular
growth, angiogenesis and sex hormone synthesis in ovarian tissue. When the balance …

Oxidative stress in oocyte aging and female reproduction

L Wang, J Tang, L Wang, F Tan, H Song… - Journal of cellular …, 2021 - Wiley Online Library
In a healthy body, reactive oxygen species (ROS) and antioxidants remain balanced. When
the balance is broken toward an overabundance of ROS, oxidative stress appears and may …

The effects of oxidative stress on female reproduction: a review

A Agarwal, A Aponte-Mellado, BJ Premkumar… - Reproductive biology …, 2012 - Springer
Oxidative stress (OS), a state characterized by an imbalance between pro-oxidant molecules
including reactive oxygen and nitrogen species, and antioxidant defenses, has been …

Redox imbalance in age-related ovarian dysfunction and perspectives for its prevention

F Timóteo-Ferreira, D Abreu, S Mendes, L Matos… - Ageing Research …, 2021 - Elsevier
The age at which women have their first child is increasing. This change represents a major
health problem to society because advanced maternal age is related with a decay in fertility …

Oxidative damage increases and antioxidant gene expression decreases with aging in the mouse ovary

J Lim, U Luderer - Biology of reproduction, 2011 - academic.oup.com
Oxidative stress has been implicated in various aspects of aging, but the role of oxidative
stress in ovarian aging remains unclear. Our previous studies have shown that the initiation …

Oxidative stress and human ovarian response—from somatic ovarian cells to oocytes damage: a clinical comprehensive narrative review

V Immediata, C Ronchetti, D Spadaro, F Cirillo… - Antioxidants, 2022 - mdpi.com
Basic scientific research on human reproduction and oxidative damage has been
extensively performed; however, a more clinical view is still lacking. As a result, exhaustive …

Oxidative stress and female reproductive disorder: A review

K Manokaran, P Bhat, D Nayak… - Asian Pacific Journal …, 2022 - journals.lww.com
Oxidative stress arises from an imbalance between the body's pro-oxidants and
antioxidants. Recently, oxidative stress has been proven a contributing factor to many …

Role of oxidative stress in female reproduction

A Agarwal, S Gupta, RK Sharma - Reproductive biology and …, 2005 - Springer
In a healthy body, ROS (reactive oxygen species) and antioxidants remain in balance. When
the balance is disrupted towards an overabundance of ROS, oxidative stress (OS) occurs …

Oxidative stress and the ovary

HR Behrman, PH Kodaman… - Journal of the Society …, 2001 - journals.sagepub.com
Superoxide (O2-), hydrogen preoxide (H2O2), and lipid peroxides are generated in luteal
tissue during natural and prostaglandin-induced regression in the rat, and this response is …