Human papillomavirus genome integration in squamous carcinogenesis: what have next‐generation sequencing studies taught us?
IJ Groves, N Coleman - The Journal of pathology, 2018 - Wiley Online Library
Human papillomavirus (HPV) infection is associated with∼ 5% of all human cancers,
including a range of squamous cell carcinomas. Persistent infection by high‐risk HPVs …
including a range of squamous cell carcinomas. Persistent infection by high‐risk HPVs …
Multi‐omics data reveals novel impacts of human papillomavirus integration on the epigenomic and transcriptomic signatures of cervical tumorigenesis
X Zeng, Y Wang, B Liu, X Rao, C Cao… - Journal of Medical …, 2023 - Wiley Online Library
Integration of human papilloma virus (HPV) DNA into the human genome may progressively
contribute to cervical carcinogenesis. To explore how HPV integration affects gene …
contribute to cervical carcinogenesis. To explore how HPV integration affects gene …
A comprehensive analysis of HPV integration loci in anogenital lesions combining transcript and genome-based amplification techniques
C Ziegert, N Wentzensen, S Vinokurova, F Kisseljov… - Oncogene, 2003 - nature.com
Persistent infections with high-risk human papillomaviruses (HPVs) induce dysplastic
lesions of the lower genital tract. Some of these lesions eventually progress to invasive …
lesions of the lower genital tract. Some of these lesions eventually progress to invasive …
[HTML][HTML] Human papillomavirus type 16 integration analysis by real-time PCR assay in associated cancers
Human papillomavirus (HPV) is a common viral infection worldwide associated with a
variety of cancers. The integration of the HPV genome in these patients causes …
variety of cancers. The integration of the HPV genome in these patients causes …
Genomic structures and regulation patterns at HPV integration sites in cervical cancer
Human papillomavirus (HPV) integration has been implicated in transforming HPV infection
into cancer, but its genomic consequences have been difficult to study using short-read …
into cancer, but its genomic consequences have been difficult to study using short-read …
Human papilloma viruses and cervical tumours: mapping of integration sites and analysis of adjacent cellular sequences
E Klimov, S Vinokourova, E Moisjak, E Rakhmanaliev… - BMC cancer, 2002 - Springer
Background In cervical tumours the integration of human papilloma viruses (HPV) transcripts
often results in the generation of transcripts that consist of hybrids of viral and cellular …
often results in the generation of transcripts that consist of hybrids of viral and cellular …
Whole genome sequencing reveals complexity in both HPV sequences present and HPV integrations in HPV-positive oropharyngeal squamous cell carcinomas
G Gao, J Wang, JL Kasperbauer, NM Tombers, F Teng… - BMC cancer, 2019 - Springer
Background High risk human papillomaviruses (HPV) plays important roles in the
development of cervical cancer, a number of other anogenital cancer and they are …
development of cervical cancer, a number of other anogenital cancer and they are …
Direct comparison of HPV16 viral genomic integration, copy loss, and structural variants in oropharyngeal and uterine cervical cancers reveal distinct relationships to …
TP Schrank, S Kim, H Rehmani, A Kothari, D Wu… - Cancers, 2022 - mdpi.com
Simple Summary HPV16 causes approximately 60% of uterine cervical cancer and 95% of
HPV-driven oropharynx cancers. Despite both being HPV-associated, these tumors are very …
HPV-driven oropharynx cancers. Despite both being HPV-associated, these tumors are very …
Mapping and analysis of HPV16 integration sites in a head and neck cancer cell line
CCR Ragin, SC Reshmi… - International journal of …, 2004 - Wiley Online Library
Human papillomavirus (HPV) is a circular double‐stranded DNA virus implicated in at least
90% of cervical and anogenital cancers and has been observed in approximately 20% of …
90% of cervical and anogenital cancers and has been observed in approximately 20% of …
[HTML][HTML] Comprehensive mapping of the human papillomavirus (HPV) DNA integration sites in cervical carcinomas by HPV capture technology
Y Liu, Z Lu, R Xu, Y Ke - Oncotarget, 2016 - ncbi.nlm.nih.gov
Integration of human papillomavirus (HPV) DNA into the host genome can be a driver
mutation in cervical carcinoma. Identification of HPV integration at base resolution has been …
mutation in cervical carcinoma. Identification of HPV integration at base resolution has been …