Studies on apolipoprotein (a) phenotypes. Part 2. Phenotype frequencies and Lp (a) concentrations in different phenotypes in patients with angiographically defined …

A Abe, A Noma, YJ Lee, H Yamaguchi - Atherosclerosis, 1992 - Elsevier
In the present paper, we have evaluated serum Lp (a) concentrations, the frequencies of Lp
(a) phenotypes and alleles and the association between the Lp (a) phenotypes and serum …

Studies on apolipoprotein (a) phenotypes. Part 1. Phenotype frequencies in a healthy Japanese population

A Abe, A Noma - Atherosclerosis, 1992 - Elsevier
The frequency distribution for serum lipoprotein (a)(Lp (a)) concentrations in healthy
Japanese was highly skewed, with a mean±SD of 14.6±13.6 mg/dl and a median of 11.0 …

Apolipoprotein (a) phenotypes, Lp (a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population: evidence for the role of the …

CH Sandholzer, E Boerwinkle, N Saha… - The Journal of …, 1992 - Am Soc Clin Investig
Elevated lipoprotein (a)(Lp [a]) concentrations are associated with premature coronary heart
disease (CHD). In the general population, Lp (a) levels are largely determined by alleles at …

Lp (a) concentration and apo (a) isoform size. Relation to the presence of coronary artery disease in familial hypercholesterolemia.

JF Bowden, PH Pritchard, JS Hill… - … and Thrombosis: A …, 1994 - Am Heart Assoc
We studied the relation between the concentration of lipoprotein (a)[Lp (a)] in plasma,
apolipoprotein (a)[apo (a)] phenotype, and the clinical expression of coronary artery disease …

Apo (a) isoforms predict risk for coronary heart disease. A study in six populations.

C Sandholzer, N Saha, JD Kark, A Rees… - … and thrombosis: a …, 1992 - Am Heart Assoc
Elevated concentrations of lipoprotein (a)(Lp [a]) in plasma are associated with premature
coronary heart disease (CHD). Lp (a) levels are largely determined by alleles at the …

Apolipoprotein (a) phenotypes as genetic markers of coronary atherosclerosis severity

C Gazzaruso, D Geroldi, A Garzaniti, C Falcone… - International journal of …, 1998 - Elsevier
We investigated Lp (a) levels and apo (a) polymorphism in relation to the severity of
coronary artery disease, expressed both by the number of coronary arteries stenosed and …

Genetic variation in lipoprotein (a) levels in families enriched for coronary artery disease is determined almost entirely by the apolipoprotein (a) gene locus.

CA DeMeester, X Bu, RJ Gray, AJ Lusis… - American journal of …, 1995 - ncbi.nlm.nih.gov
Abstract Lipoprotein (a)(Lp [a]) is a cholesterol-rich lipoprotein resembling LDL but also
containing a large polypeptide designated apolipoprotein (a)(apo [a]). Its levels are highly …

Sequence polymorphisms in the apolipoprotein (a) gene and their association with lipoprotein (a) levels and myocardial infarction. The ECTIM Study

L Brazier, L Tiret, G Luc, D Arveiler, JB Ruidavets… - Atherosclerosis, 1999 - Elsevier
Lp (a) concentrations are largely determined by apo (a) isoform size, but several studies
have shown that apo (a) isoforms could not entirely explain the increase of Lp (a) levels …

High degree of genetic polymorphism in apolipoprotein (a) associated with plasma lipoprotein (a) levels in Japanese and Chinese populations

S Kikuchi, A Nakagawa, K Kobayashi, L Li, H Yanagi… - Human genetics, 1993 - Springer
We have developed a sensitve, high-resolution method for the analysis of the apolipoprotein
(a)[apo (a)] isoforms using sodium dodecyl sulfate (SDS)-agarose/gradient polyacrylamide …

Genetics of the quantitative Lp (a) lipoprotein trait: III. Contribution of Lp (a) glycoprotein phenotypes to normal lipid variation

E Boerwinkle, HJ Menzel, HG Kraft, G Utermann - Human genetics, 1989 - Springer
Summary Apolipoprotein (a)[apo (a)] is a large serum glycoprotein with several genetically
determined isoforms differing in their apparent molecular weight. We determined the effects …