[PDF][PDF] Apolipoprotein (a) phenotypes predict the severity of coronary artery stenosis

J Ducas, C Silversides, TC Dembinski… - Clinical and …, 2002 - researchgate.net
Background: Studies on the impact of elevated levels of lipoprotein (a)(Lp [a]) or
apolipoprotein (a)(apo [a]) on the development of coronary artery disease have given …

Evidence that apolipoprotein (a) phenoptype is a risk factor for coronary artery disease in men< 55 years of age

M Parlavecchia, A Pancaldi, R Taramelli… - The American journal of …, 1994 - Elsevier
Whereas the importance of plasma lipoprotein (a)[Lp (a)] levels as a risk factor for premature
coronary artery disease (CAD) is certain, it is not clear if the apolipoprotein (a)[apo (a)] …

Molecular analysis of apo (a) fragmentation in polygenic hypercholesterolemia: characterization of a new plasma fragment pattern

S Gonbert, B Saint-Jore, P Giral, C Doucet… - … , and vascular biology, 2001 - Am Heart Assoc
Hypercholesterolemia is frequently associated with elevated Lp (a) levels, an independent
risk factor for coronary, cerebrovascular, and peripheral vascular disease. A portion of …

Studies of apolipoprotein (a) promoter from subjects with different plasma lipoprotein (a) concentrations

JH Wu, IN Lee - Clinical biochemistry, 2003 - Elsevier
OBJECTIVE: High plasma lipoprotein (a)[Lp (a)] level is closely related to coronary heart
disease and cerebral thrombosis. The Lp (a) concentration is determined primarily by …

Molecular definition of the extreme size polymorphism in apolipoprotein (a)

C Lackner, JC Cohen, HH Hobbs - Human molecular genetics, 1993 - academic.oup.com
Abstract Lipoprotein (a)[Lp (a)], an atherogenic lipoprotein, consists of an LDL particle
complexed with a large glycoprotein, apollpoprotein (a)[apo (a)]. Apo (a) is one of the most …

Association of lipoprotein (a) levels and apolipoprotein (a) phenotypes with coronary artery disease in type 2 diabetic patients and in non‐diabetic subjects

C Gazzaruso, A Garzaniti, C Falcone… - Diabetic …, 2001 - Wiley Online Library
Aims We investigated whether in Type 2 diabetic patients lipoprotein (a)(Lp (a)) levels and
apolipoprotein (a)(apo (a)) polymorphism are associated with angiographically documented …

Molecular basis of apolipoprotein (a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresis.

C Lackner, E Boerwinkle, CC Leffert… - The Journal of …, 1991 - Am Soc Clin Investig
Lipoprotein (a)[Lp (a)] is a cholesterol-rich lipoprotein that is distinguished by its content of a
glycoprotein called apolipoprotein (a)[apo (a)]. Apo (a) varies in size among individuals …

Association of elevated lipoprotein (a) levels and coronary heart disease in NIDDM patients. Relationship with apolipoprotein (a) phenotypes

J Ruiz, J Thillet, T Huby, RW James, D Erlich, P Flandre… - Diabetologia, 1994 - Springer
Non-insulin-dependent diabetes mellitus (NIDDM) is a strong and independent risk factor for
coronary heart disease. We assessed the potential relationship between plasma Lp (a) …

Lp (a) lipoprotein is a major risk factor for cardiovascular disease: pathogenic mechanisms and clinical significance

GH Dahlén, H Stenlund - Clinical genetics, 1997 - Wiley Online Library
The results of two previous and two recent studies of middle‐aged males and females are
presented to exemplify the clinical importance of lipoprotein (a)(Lp (a)) as a risk factor for …

Serum lipoprotein (a) concentrations and apolipoprotein (a) isoforms: association with the severity of clinical presentation in patients with coronary heart disease

CS Katsouras, SA Karabina… - Journal of …, 2001 - journals.sagepub.com
Objective The aim of this study was to investigate the possible associations between
lipoprotein (a)[Lp (a)] concentrations or apolipoprotein (a) isoforms and the mode of clinical …