HIV-1 drug resistance and third-line therapy outcomes in patients failing second-line therapy in Zimbabwe
C Chimbetete, D Katzenstein, T Shamu… - Open forum …, 2018 - academic.oup.com
Objectives To analyze the patterns and risk factors of HIV drug resistance mutations among
patients failing second-line treatment and to describe early treatment responses to …
patients failing second-line treatment and to describe early treatment responses to …
HIV drug resistance mutations among patients failing second-line antiretroviral therapy in Rwanda
JA Ndahimana, DJ Riedel, R Muhayimpundu… - 2016 - journals.sagepub.com
Background Studies of patients failing second-line antiretroviral therapy (ART) in resource-
limited settings (RLS) are few. Evidence suggests most patients who appear to be …
limited settings (RLS) are few. Evidence suggests most patients who appear to be …
HIV‐1 drug resistance testing at second‐line regimen failure in Arua, Uganda: avoiding unnecessary switch to an empiric third‐line
F Fily, E Ayikobua, D Ssemwanga… - Tropical Medicine & …, 2018 - Wiley Online Library
Objectives The number of patients on second‐line antiretroviral therapy is growing, but data
on HIV drug resistance patterns at failure in resource‐constrained settings are scarce. We …
on HIV drug resistance patterns at failure in resource‐constrained settings are scarce. We …
Patterns of HIV-1 drug resistance after first-line antiretroviral therapy (ART) failure in 6 sub-Saharan African countries: implications for second-line ART strategies
RL Hamers, KCE Sigaloff, AM Wensing… - Clinical infectious …, 2012 - academic.oup.com
Background. Human immunodeficiency virus type 1 (HIV-1) drug resistance may limit the
benefits of antiretroviral therapy (ART). This cohort study examined patterns of drug …
benefits of antiretroviral therapy (ART). This cohort study examined patterns of drug …
High level of HIV-1 resistance in patients failing long-term first-line antiretroviral therapy in Mali
DB Fofana, C Soulié, A Baldé… - Journal of …, 2014 - academic.oup.com
Objectives In resource-limited settings, few data are available on virological failure after long-
term first-line antiretroviral therapy. This study characterized the genotypic resistance …
term first-line antiretroviral therapy. This study characterized the genotypic resistance …
Characterization of HIV drug resistance mutations among patients failing first‐line antiretroviral therapy from a tertiary referral center in Lusaka, Zambia
L Seu, LB Mulenga, M Siwingwa… - Journal of medical …, 2015 - Wiley Online Library
In settings of resource constraint, an understanding of HIV drug resistance can guide
antiretroviral therapy (ART) at switch to second‐line therapy. To determine the prevalence of …
antiretroviral therapy (ART) at switch to second‐line therapy. To determine the prevalence of …
Characterization of HIV-1 antiretroviral drug resistance after second-line treatment failure in Mali, a limited-resources setting
AI Maiga, DB Fofana, M Cisse, F Diallo… - Journal of …, 2012 - academic.oup.com
Objectives We describe the outcomes of second-line drug resistance profiles and predict the
efficacy of drugs for third-line therapy in patients monitored without the benefit of plasma HIV …
efficacy of drugs for third-line therapy in patients monitored without the benefit of plasma HIV …
Effect of pretreatment HIV-1 drug resistance on immunological, virological, and drug-resistance outcomes of first-line antiretroviral treatment in sub-Saharan Africa: a …
RL Hamers, R Schuurman, KCE Sigaloff… - The Lancet infectious …, 2012 - thelancet.com
Background The effect of pretreatment HIV-1 drug resistance on the response to first-line
combination antiretroviral therapy (ART) in sub-Saharan Africa has not been assessed. We …
combination antiretroviral therapy (ART) in sub-Saharan Africa has not been assessed. We …
[HTML][HTML] Drug resistance in HIV patients with virological failure or slow virological response to antiretroviral therapy in Ethiopia
A Abdissa, D Yilma, J Fonager, AM Audelin… - BMC infectious …, 2014 - Springer
Background The ongoing scale-up of antiretroviral therapy (ART) in sub-Saharan Africa has
prompted the interest in surveillance of transmitted and acquired HIV drug resistance …
prompted the interest in surveillance of transmitted and acquired HIV drug resistance …
Second-line antiretroviral treatment successfully resuppresses drug-resistant HIV-1 after first-line failure: prospective cohort in Sub-Saharan Africa
KCE Sigaloff, RL Hamers, CL Wallis… - The Journal of …, 2012 - academic.oup.com
Little is known about the effect of human immunodeficiency virus type 1 (HIV-1) resistance
mutations present at time of regimen switch on the response to second-line antiretroviral …
mutations present at time of regimen switch on the response to second-line antiretroviral …