High frequency of antiviral drug resistance and non-B subtypes in HIV-1 patients failing antiviral therapy in Cuba

V Kourí, Y Alemán, L Pérez, J Pérez, C Fonseca… - Journal of clinical …, 2012 - Elsevier
BACKGROUND: Emergence of HIV-1 drug resistance may limit the sustained benefits of
antiretroviral therapy (ART) in settings with limited laboratory monitoring and drug options …

[HTML][HTML] HIV-1 drug resistance genotyping from antiretroviral therapy (ART) naïve and first-line treatment failures in Djiboutian patients

A Elmi Abar, A Jlizi, HY Darar, MABH Kacem… - Diagnostic pathology, 2012 - Springer
Abstract In this study we report the prevalence of antiretroviral drug resistant HIV-1
genotypes of virus isolated from Djiboutian patients who failed first-line antiretroviral therapy …

[HTML][HTML] Drug resistance mutations and viral load in human immunodeficiency virus type 2 and dual HIV-1/HIV-2 infected patients in Ghana

CZ Abana, KWC Sagoe, EY Bonney, EK Maina… - Medicine, 2019 - journals.lww.com
Antiretroviral therapy (ART) and drug resistance studies worldwide have focused almost
exclusively on human immunodeficiency virus type 1 (HIV-1). As a result, there is limited …

Emergence of HIV drug resistance during first-and second-line antiretroviral therapy in resource-limited settings

MC Hosseinipour, RK Gupta, G Van Zyl… - The Journal of …, 2013 - academic.oup.com
Introduction Antiretroviral therapy (ART) in resource-limited settings has expanded in the last
decade, reaching> 8 million individuals and reducing AIDS mortality and morbidity …

[HTML][HTML] Trends and correlates of HIV-1 resistance among subjects failing an antiretroviral treatment over the 2003–2012 decade in Italy

M Franzetti, M Violin, A Antinori, A De Luca… - BMC infectious …, 2014 - Springer
Background Despite a substantial reduction in virological failures following introduction of
new potent antiretroviral therapies in the latest years, drug resistance remains a limitation for …

[HTML][HTML] High levels of virological failure with major genotypic resistance mutations in HIV-1-infected children after 5 years of care according to WHO-recommended 1st …

CD Mossoro-Kpinde, JC Gody, RSM Bouassa… - Medicine, 2017 - journals.lww.com
A large cohort of 220 HIV-1-infected children (median [range] age: 12 [4–17] years) was
cared and followed up in the Central African Republic, including 198 in 1st-line and 22 in …

[HTML][HTML] HIV-1 Low-Frequency Variants Identified in Antiretroviral-Naïve Subjects with Virologic Failure after 12 Months of Follow-Up in Panama

A Moreno, C González, J Góndola, O Chavarría… - Infectious Disease …, 2023 - mdpi.com
Low-frequency mutations associated with drug resistance have been related to virologic
failure in subjects with no history of pre-treatment and recent HIV diagnosis. In total, 78 …

[HTML][HTML] Drug resistance in children at virological failure in a rural KwaZulu-Natal, South Africa, cohort

S Pillay, RM Bland, RJ Lessells, J Manasa… - AIDS research and …, 2014 - Springer
Background Better understanding of drug resistance patterns in HIV-infected children on
antiretroviral therapy (ART) is required to inform public health policies in high prevalence …

Pretreatment HIV drug resistance increases regimen switches in sub-Saharan Africa

TS Boender, BM Hoenderboom… - Clinical Infectious …, 2015 - academic.oup.com
Background. After the scale-up of antiretroviral therapy (ART) for human immunodeficiency
virus (HIV) infection in Africa, increasing numbers of patients have pretreatment drug …

[HTML][HTML] Prevalence and factors associated with HIV-1 drug resistance mutations in treatment-experienced patients in Nairobi, Kenya: A cross-sectional study

YA Scriven, MM Mulinge, N Saleri, EA Luvai… - Medicine, 2021 - journals.lww.com
An estimated 1.5 million Kenyans are HIV-seropositive, with 1.1 million on antiretroviral
therapy (ART), with the majority of them unaware of their drug resistance status. In this study …