Circulating dipeptidyl peptidase-4 activity is associated with insulin resistance in type 1 diabetic patients

K Blaslov, T Bulum, L Duvnjak - Journal of diabetes and its complications, 2015 - Elsevier
Aim The pathophysiology of insulin resistance (IR) comprises a complex adipokine
mediated cross-talk between white adipose tissue and other organs. Dipeptidyl peptidase-4 …

Fasting serum dipeptidyl peptidase-4 activity is independently associated with alanine aminotransferase in type 1 diabetic patients

K Blaslov, T Bulum, J Knežević-Ćuća, L Duvnjak - Clinical biochemistry, 2015 - Elsevier
Abstract Objectives Dipeptidyl peptidase-4 (DPP4) was recently proposed as a novel
adipokine linked to insulin resistance (IR). As IR represents a cluster of disorders in hepatic …

Dipeptidyl peptidase-4 activity is associated with urine albumin excretion in type 1 diabetes

L Duvnjak, MN Perković, K Blaslov - Journal of Diabetes and its …, 2017 - Elsevier
Aims The inability of kidneys to prevent urinary protein leakage represents the earliest sign
of renal damage in diabetic kidney disease (DKD). Recent data suggest the possible …

Significant elevation of serum dipeptidyl peptidase-4 activity in young-adult type 1 diabetes

S Osawa, D Kawamori, N Katakami, M Takahara… - Diabetes Research and …, 2016 - Elsevier
Aims Currently, inhibition of dipeptidyl peptidase-4 (DPP-4) is widely used in the treatment of
type 2 diabetes. Application of this strategy is awaited as a new therapeutic approach for …

The increased dipeptidyl peptidase‐4 activity is not counteracted by optimized glucose control in type 2 diabetes, but is lower in metformin‐treated patients

GP Fadini, M Albiero, L Menegazzo… - Diabetes, Obesity …, 2012 - Wiley Online Library
Aim: Dipeptidyl peptidase (DPP)‐4 in responsible for incretin degradation and some
observations suggest that DPP‐4 activity is increased in type 2 diabetes (T2D). We aimed to …

Dipeptidyl peptidase 4 activity is related to body composition, measures of adiposity, and insulin resistance in subjects with excessive adiposity and different degrees …

WS Silva Junior, MGC Souza… - Journal of diabetes …, 2019 - Wiley Online Library
Background. The enzyme dipeptidyl peptidase 4 (DPP4) has been recently recognized as
an adipo‐myokine. However, studies that associate its constitutive activity with body …

[PDF][PDF] Soluble dipeptidyl peptidase-4 levels are associated with decreased renal function in patients with type 2 diabetes mellitus

EH Cho, SW Kim - Diabetes & Metabolism Journal, 2019 - synapse.koreamed.org
Background: Dipeptidyl peptidase-4 (DPP-4) is strongly expressed in the kidney, and
soluble levels of this protein are used as a marker in various chronic inflammatory diseases …

[HTML][HTML] Increased plasma dipeptidyl peptidase-4 (DPP4) activity is an obesity-independent parameter for glycemic deregulation in type 2 diabetes patients

J Sarkar, T Nargis, O Tantia, S Ghosh… - Frontiers in …, 2019 - frontiersin.org
Background: Increase in circulating dipeptidyl peptidase-4 (DPP4) activity and levels has
been reported to associate both with hyperglycemia and obesity. Here we aim to decipher …

Elevated serum dipeptidyl peptidase-4 activity in type 1 diabetes mellitus: a direct comparison

T Varga, G Firneisz, G Nagy, A Somogyi - Orvosi Hetilap, 2010 - akjournals.com
Dipeptidyl peptidase-4 (DPP-4) has an important role in the carbohydrate metabolism with
the degradation of incretin hormones. Aim: We assessed the serum DPP-4 activity both in …

High circulating plasma dipeptidyl peptidase-4 levels in non-obese Asian Indians with type 2 diabetes correlate with fasting insulin and LDL-C levels, triceps skinfolds …

S Anoop, A Misra, SP Bhatt, S Gulati… - BMJ open diabetes …, 2017 - drc.bmj.com
Aim To evaluate circulating plasma dipeptidyl peptidase-4 (DPP4) levels in non-obese
Asian Indians with type 2 diabetes mellitus (T2DM), and to correlate these with metabolic …