Reviewing long-term antidepressants can reduce drug burden: a prospective observational cohort study

CF Johnson, HJ Macdonald, P Atkinson… - British Journal of …, 2012 - bjgp.org
Background Antidepressant prescribing continues to rise. Contributing factors are increased
long-term prescribing and possibly the use of higher selective serotonin re-uptake inhibitor …

What proportion of initially prescribed antidepressants is still being prescribed chronically after 5 years in general practice? A longitudinal cohort analysis

PFM Verhaak, D de Beurs, P Spreeuwenberg - BMJ open, 2019 - bmjopen.bmj.com
Objectives Antidepressant prescribing almost doubled in the Netherlands between 1996
and 2012, which could be accounted for by longer continuation after the first prescription …

Factors associated with duration of new antidepressant treatment: analysis of a large primary care database

C Burton, N Anderson, K Wilde, CR Simpson - British Journal of General …, 2012 - bjgp.org
Background It is not known how much the duration of newly prescribed antidepressant
treatment is influenced by patient characteristics or practice variation. Aim To describe the …

Antidepressant use in clinical practice: efficacy v. effectiveness

J Donoghue, TR Hylan - The British Journal of Psychiatry, 2001 - cambridge.org
BackgroundAlthough the efficacy of antidepressants has been demonstrated in randomised,
controlled clinical trials, it is how an antidepressant is used in clinical practice that …

[HTML][HTML] Withdrawal of unnecessary antidepressant medication: a randomised controlled trial in primary care

R Eveleigh, E Muskens, P Lucassen, P Verhaak… - BJGP open, 2018 - bjgpopen.org
Background Antidepressant use has increased exponentially in recent decades, mostly due
to long continuation. Aim To assess the effectiveness of a tailored recommendation to …

Initiation and duration of selective serotonin reuptake inhibitor prescribing over time: UK cohort study

RL McCrea, CJ Sammon, I Nazareth… - The British Journal of …, 2016 - cambridge.org
BackgroundRecent media reports have focused on the large increase in antidepressants
dispensed in England. We investigated this, focusing on selective serotonin reuptake …

Long-term and short-term antidepressant use in general practice: data from a large cohort in the Netherlands

KM Huijbregts, AW Hoogendoorn, P Slottje… - Psychotherapy and …, 2017 - karger.com
Background: Antidepressant use is highly prevalent. Research has mainly focused on
efficacy during short periods of use for depression and anxiety. There is a relative paucity of …

Influences on antidepressant prescribing trends in the UK: 1995–2011

B Mars, J Heron, D Kessler, NM Davies… - Social psychiatry and …, 2017 - Springer
Purpose The number of antidepressants prescribed in the UK has been increasing over the
last 25 years; however, the reasons for this are not clear. This study examined trends in …

Antidepressant medication prescribing patterns in Irish general practice from 2016 to 2020 to assess for long-term use

A McCool, K Lukas, P Hayes, D Kelly - Irish Journal of Medical Science …, 2021 - Springer
Background/aims The aim of this study was to identify the trends in antidepressant (AD)
medication use in two Irish general practices over a 5-year period, 2016 to 2020. The …

Trends in primary care antidepressant prescribing 1995-2007: a longitudinal population database analysis

P Lockhart, B Guthrie - British Journal of General Practice, 2011 - bjgp.org
Background Antidepressant prescribing is increasing worldwide, prompting policy
interventions and targets to halt the rise. Aim To examine time trends in GP antidepressant …