Thalamic deactivation at sleep onset precedes that of the cerebral cortex in humans

M Magnin, M Rey, H Bastuji… - Proceedings of the …, 2010 - National Acad Sciences
Thalamic and cortical activities are assumed to be time-locked throughout all vigilance
states. Using simultaneous intracortical and intrathalamic recordings, we demonstrate here …

Neural basis of alertness and cognitive performance impairments during sleepiness II. Effects of 48 and 72 h of sleep deprivation on waking human regional brain …

ML Thomas, HC Sing, G Belenky… - Thalamus & related …, 2003 - cambridge.org
Sleep deprivation impairs alertness and cognitive performance, and these deficits suggest
decreases in brain activity and function, particularly in the prefrontal cortex, a region …

Conscious and pre-conscious processes as seen from the standpoint of sleep-waking cycle neurophysiology

D Pare, R Llinás - Neuropsychologia, 1995 - Elsevier
The literature on state-dependent fluctuations in thalamocortical activities indicates that in
electrophysiological terms, waking and paradoxical sleep are fundamentally identical states …

Interplay between spontaneous and induced brain activity during human non-rapid eye movement sleep

TT Dang-Vu, M Bonjean, M Schabus… - Proceedings of the …, 2011 - National Acad Sciences
Humans are less responsive to the surrounding environment during sleep. However, the
extent to which the human brain responds to external stimuli during sleep is uncertain. We …

Sleep, consciousness and the spontaneous and evoked electrical activity of the brain. Is there a cortical integrating mechanism?

BM Evans - Neurophysiologie Clinique/Clinical Neurophysiology, 2003 - Elsevier
The physiological mechanisms that underlie consciousness and unconsciousness are the
sleep/wake mechanisms. Deep sleep is a state of physiological reversible unconsciousness …

The transition from slow-wave sleep to paradoxical sleep: evolving facts and concepts of the neurophysiological processes underlying the intermediate stage of sleep

C Gottesmann - Neuroscience & Biobehavioral Reviews, 1996 - Elsevier
GOTTESMANN, C. The transition from slow-wave sleep to paradoxical sleep: Evolving facts
and concepts of the neurophysiological processes underlying the intermediate stage of …

[HTML][HTML] Brain dynamics during the sleep onset transition: an EEG source localization study

AF Guerrero, P Achermann - Neurobiology of sleep and circadian rhythms, 2019 - Elsevier
EEG source localization is an essential tool to reveal the cortical sources underlying brain
oscillatory activity. We applied LORETA, a technique of EEG source localization, to identify …

Decreased connectivity between the thalamus and the neocortex during human nonrapid eye movement sleep

D Picchioni, ML Pixa, M Fukunaga, WS Carr… - Sleep, 2014 - academic.oup.com
Abstract Study Objectives: To determine whether thalamocortical signaling between the
thalamus and the neocortex decreases from wakefulness to nonrapid eye movement …

Local aspects of sleep: observations from intracerebral recordings in humans

L Nobili, L De Gennaro, P Proserpio, F Moroni… - Progress in brain …, 2012 - Elsevier
Human sleep is considered a global phenomenon, orchestrated by central specialized
neuronal networks modulating the whole-brain activity. However, recent studies point to a …

Human cortical excitability increases with time awake

R Huber, H Mäki, M Rosanova, S Casarotto… - Cerebral …, 2013 - academic.oup.com
Prolonged wakefulness is associated not only with obvious changes in the way we feel and
perform but also with well-known clinical effects, such as increased susceptibility to seizures …